[HTML][HTML] Utilizing the Centiloid scale in cross-sectional and longitudinal PiB PET studies
Amyloid imaging is a valuable tool for research and diagnosis in dementing disorders.
Successful use of this tool is limited by the lack of a common standard in the quantification of …
Successful use of this tool is limited by the lack of a common standard in the quantification of …
Validation of amyloid PET positivity thresholds in centiloids: a multisite PET study approach
Background Inconsistent positivity thresholds, image analysis pipelines, and quantitative
outcomes are key challenges of multisite studies using more than one β-amyloid (Aβ) …
outcomes are key challenges of multisite studies using more than one β-amyloid (Aβ) …
Implementing the centiloid transformation for 11C-PiB and β-amyloid 18F-PET tracers using CapAIBL
The centiloid scale was recently proposed to provide a standard framework for the
quantification of β-amyloid PET images, so that amyloid burden can be expressed on a …
quantification of β-amyloid PET images, so that amyloid burden can be expressed on a …
Software development for quantitative analysis of brain amyloid PET
H Matsuda, T Yamao - Brain and behavior, 2022 - Wiley Online Library
Introduction Centiloid (CL) scaling has become a standard quantitative measure in amyloid
PET because it allows the direct comparison of results across sites, even when different …
PET because it allows the direct comparison of results across sites, even when different …
Quantification of amyloid PET for future clinical use: a state-of-the-art review
Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer's
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …
Comparison of amyloid PET measured in Centiloid units with neuropathological findings in Alzheimer's disease
Abstract Background The Centiloid scale was developed to standardise the results of beta-
amyloid (Aβ) PET. We aimed to determine the Centiloid unit (CL) thresholds for CERAD …
amyloid (Aβ) PET. We aimed to determine the Centiloid unit (CL) thresholds for CERAD …
The Centiloid Project: standardizing quantitative amyloid plaque estimation by PET
Although amyloid imaging with PiB-PET ([C-11] Pittsburgh Compound-B positron emission
tomography), and now with F-18-labeled tracers, has produced remarkably consistent …
tomography), and now with F-18-labeled tracers, has produced remarkably consistent …
Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET
RATIONALE:[11C] Pittsburgh compound-B (PIB) has been the most widely used positron
emission tomography (PET) imaging agent for brain amyloid. Several longitudinal studies …
emission tomography (PET) imaging agent for brain amyloid. Several longitudinal studies …
[HTML][HTML] Effect of age, ethnicity, sex, cognitive status and APOE genotype on amyloid load and the threshold for amyloid positivity
The threshold for amyloid positivity by visual assessment on PET has been validated by
comparison to amyloid load measured histopathologically and biochemically at post …
comparison to amyloid load measured histopathologically and biochemically at post …
Quantitative amyloid imaging in autosomal dominant Alzheimer's disease: results from the DIAN study group
Amyloid imaging plays an important role in the research and diagnosis of dementing
disorders. Substantial variation in quantitative methods to measure brain amyloid burden …
disorders. Substantial variation in quantitative methods to measure brain amyloid burden …