Mounting evidence suggests that aberrations in immune-inflammatory pathways contribute
to the pathophysiology of major depressive disorder (MDD), and individuals with MDD may …

Predicting antidepressant treatment response has been a clinical challenge for major
depressive disorder (MDD). The inflammation hypothesis of depression suggests that …

Abstract Introduction Major Depressive Disorder (MDD) in accordance to the inflammatory
concept is associated with complex immunological disturbances in the central nervous …

Objective To conduct a systematic review and meta‐analysis of studies that measured
cytokine and chemokine levels in individuals with major depressive disorder (MDD) …

Major depressive disorder (MDD) is a common condition that afflicts the general population
across a broad spectrum of ages and social backgrounds. The inflammatory hypothesis of …

Objective: Altered levels of peripheral inflammatory and proinflammatory cytokine markers
affect the different clinical stages of major depressive disorder (MDD). A concrete …

Cytokines have been implicated in the pathology of depression. Currently, the evidence is
based on cross-sectional studies and meta-analytic research comparing blood …

Recognition that inflammation may represent a common mechanism of disease has been
extended to include neuropsychiatric disorders including major depression. Patients with …

Objectives The literature exploring the role that cytokine functioning plays in the
pathogenesis and treatment of depressive illness is reviewed. The review focuses on the …

BackgroundCross-sectional studies support an association between depression and
inflammatory markers. However, little is known of their relationship in the context of …