Background: inflammasome protein govern the inflammatory process. The elevation of
NLRP3 inflammasome might be related to bad seminal fluid analysis results. Objectives …

Background Varicocele is a common cause of male infertility with multifactorial etiology.
Inflammation is a characteristic pathological event that occurs in the testis tissue following …

Background/aim: Mechanisms to explain inflammation in male infertility of unknown cause
are still being investigated. The inflammasome is a key regulator of innate immunity in the …

METHODS Semen was obtained from men with abnormal semen parameters who were
being evaluated in an infertility clinic (n= 131). Each of these men was assigned to a group …

Infertility is defined as the inability of couples to have a baby without contraception after at
least 1 year of regular sexual intercourse. Mechanisms to explain inflammation in male …

Objective The activation of the NLRP3 inflammasome has been implicated in male infertility.
Our study aimed to investigate the therapeutic role of Thiolutin (THL), an inhibitor of the …

Background: The majority of male patients with spinal cord injury (SCI) suffer from infertility.
Nucleotide-binding oligomerization domain-like receptors NOD-like receptors (NLRs) are a …

The inflammasomes are a family of recently described multi-protein cytoplasmic sensors that
orchestrate the inflammatory response and participate in a variety of inflammatory …

During the last decades, a wide range of factors involved in the physiopathology of male
infertility disease have been discussed. The inflammation role in some of the main infertility …

An appropriate immune response by seminal plasma (SP) is essential for a successful
pregnancy and is regarded as a sterile inflammatory response. In contrast, the overactivation …