Rationale: Esophageal manometry is the clinically available method to estimate pleural
pressure, thus enabling calculation of transpulmonary pressure (Pl). However, many …

Acute lung injury can be worsened by inappropriate mechanical ventilation, and numerous
experimental studies suggest that ventilator-induced lung injury is increased by excessive …

Objective: Pressure inflating the lung during mechanical ventilation is the difference
between pressure applied at the airway opening (P ao) and pleural pressure (P pl) …

This report summarizes current physiological and technical knowledge on esophageal
pressure (Pes) measurements in patients receiving mechanical ventilation. The respiratory …

Respiratory mechanics refers to the expression of lung function through measures of
pressure and flow. From these measurements, a variety of derived indices can be …

Objective To evaluate the ability of three indices derived from the airway pressure curve for
titrating positive end-expiratory pressure (PEEP) to minimize mechanical stress while …

Ventilator management decisions in acute lung injury could be better informed with
knowledge of the patient's transpulmonary pressure, which can be estimated using …

Objectives: 1) To compare two published methods for estimating pleural pressure, one
based on directly measured esophageal pressure and the other based on chest wall …

We aimed to elucidate the relationships between pleural (Ppl), esophageal (Pes), and
superimposed gravitational pressures in acute lung injury, and to understand the …

Abstract Purpose Esophageal pressure (Pes) is a minimally invasive advanced respiratory
monitoring method with the potential to guide management of ventilation support and …