Abstract Purpose Paraoxonase-1 (PON1) is a lipolactonase implicated in the elimination of
carcinogenic free radicals and in the scavenging mechanisms to maintain oxidative balance …

The paraoxonase (PON) gene family includes three proteins, PON1, PON2 and PON3.
PON1 and PON3 are both associated with high-density lipoprotein (HDL) particles and exert …

Abstract Human serum paraoxonase 1 (PON1, EC 3.1. 1.2) is a high density lipoprotein
(HDL)-associated antioxidant enzyme that not only decreases oxidative stress, but it is also …

PON2 belongs to the paraoxonase protein family that consists of lactone hydrolyzing
enzymes with different substrate specificities. Unlike other members of the family, PON2 …

Paraoxonase-2 (PON2) is a ubiquitously expressed intracellular protein that is localized in
the perinuclear region, the endoplasmic reticulum (ER), and mitochondria, and is also …

Paraoxonase-1 (PON1) is an intra-cellular antioxidant enzyme found also in the circulation
associated with high-density lipoproteins. The activity of this enzyme has been shown to be …

Exploring the role of Paraoxonase-2 in bladder cancer: analyses performed on tissue samples,
urines and cell culturess - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Extensive research has been carried out to understand and elucidate the mechanisms of
paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular …

Oral squamous cell carcinoma (OSCC) is the most common head and neck squamous
carcinoma (HNSCC) and is characterized by high aggressiveness and metastatic potential …

Objectives Oxidative stress is well recognized to play a role in the pathogenesis of many
diseases, including cancers. Paraoxonase-1 (PON1) is implicated in the elimination of …