Dementia risk and prevention by targeting modifiable vascular risk factors

S Tariq, PA Barber - Journal of neurochemistry, 2018 - Wiley Online Library
The incidence of dementia is expected to double in the next 20 years and will contribute to
heavy social and economic burden. Dementia is caused by neuronal loss that leads to brain …

[HTML][HTML] Dementia prevention: current epidemiological evidence and future perspective

F Mangialasche, M Kivipelto, A Solomon… - Alzheimer's research & …, 2012 - Springer
Dementia, a major cause of disability and institutionalization in older people, poses a
serious threat to public health and to the social and economic development of modern …

Can dementia be prevented? Brain aging in a population-based context

MN Haan, R Wallace - Annu. Rev. Public Health, 2004 - annualreviews.org
As a consequence of global aging of the human population, the occurrence of cognitive
impairment and dementia is rapidly becoming a significant burden for medical care and …

Preventing Alzheimer's disease by targeting vascular risk factors: hope and gap

C Qiu - Journal of Alzheimer's Disease, 2012 - content.iospress.com
Alzheimer's disease (AD) is a major cause of functional dependence, poor quality of life,
institutionalization, and mortality among elderly people. As a multifactorial disorder, AD has …

Treating vascular risk factors and maintaining vascular health: is this the way towards successful cognitive ageing and preventing cognitive decline?

K Alagiakrishnan, P McCracken… - Postgraduate medical …, 2006 - academic.oup.com
Dementia is a progressive disorder that typically worsens with time and from which recovery
is unlikely. The incidence of dementia increases exponentially with ageing and is an …

[HTML][HTML] METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for …

M Dichgans, J Wardlaw, E Smith, V Zietemann… - Alzheimer's & …, 2016 - Elsevier
Dementia is a global problem and major target for health care providers. Although up to 45%
of cases are primarily or partly due to cerebrovascular disease, little is known of these …

[HTML][HTML] Shared risk factors between dementia and atherosclerotic cardiovascular disease

LT Nordestgaard, M Christoffersen… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease is the most common form of dementia, and the prodromal phases of
Alzheimer's disease can last for decades. Vascular dementia is the second most common …

[HTML][HTML] Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health …

A Solomon, R Stephen, D Altomare, E Carrera… - Alzheimer's research & …, 2021 - Springer
Although prevention of dementia and late-life cognitive decline is a major public health
priority, there are currently no generally established prevention strategies or operational …

[HTML][HTML] The pathobiology of vascular dementia

C Iadecola - Neuron, 2013 - cell.com
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …

Roles of vascular risk factors in the pathogenesis of dementia

S Takeda, H Rakugi, R Morishita - Hypertension Research, 2020 - nature.com
The number of people with dementia is rapidly growing along with the aging of society and
is becoming a social issue worldwide. The results of recent clinical and basic studies have …