HTLV-1 proviral load in cerebrospinal fluid may not be a good marker to differentiate asymptomatic carriers with high proviral load in blood from HAM/TSP patients

ML Martins, AB de Freitas Carneiro-Proietti… - Journal of …, 2018 - Springer
An elevated human T cell leukemia virus type 1 (HTLV-1) proviral load (PVL) is an important
risk factor for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

Long-term follow-up of HTLV-1 proviral load in asymptomatic carriers and in incident cases of HAM/TSP: what is its relevance as a prognostic marker for neurologic …

ML Martins, JC Guimarães, JG Ribas… - Journal of …, 2017 - Springer
Abstract HTLV-1 proviral load (pvl) is an important risk marker for HTLV-1-associated
myelopathy/tropical spastic paraparesis (HAM/TSP), but its value as prognostic marker is not …

Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers: high proviral load strongly predisposes to HAM/TSP

M Nagai, K Usuku, W Matsumoto, D Kodama… - Journal of …, 1998 - Taylor & Francis
In order to examine the effect of HTLV-I proviral load on the pathogenesis of HAM/TSP, we
measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a …

Neurologic, clinical, and immunologic features in a cohort of HTLV-1 carriers with high proviral loads

SN Ferraz, GF Costa, JA Carneiro Neto, T Hebert… - Journal of …, 2020 - Springer
A high proviral load (PVL) is recognized as a risk factor for human T cell leukemia virus-1-
associated myelopathy/tropical spastic paraparesis (HAM/TSP), but there is a lack of …

Monitoring the HTLV‐1 proviral load in the peripheral blood of asymptomatic carriers and patients with HTLV‐associated myelopathy/tropical spastic paraparesis from …

MSBS Furtado, RG Andrade… - Journal of medical …, 2012 - Wiley Online Library
Human T‐lymphotropic virus 1 (HTLV‐1) infection is associated with HTLV‐associated
myelopathy/tropical spastic paraparesis (HAM/TSP), which affects approximately 5% of …

Human T cell lymphotropic virus type 1 (HTLV‐1) proviral load of HTLV‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients according to new …

MFR Grassi, VN Olavarria… - Journal of medical …, 2011 - Wiley Online Library
A high human T‐cell lymphotropic virus type 1 (HTLV‐1) proviral load is described in HTLV‐
1‐associated diseases, especially HAM/TSP. However, the cut‐off value to define high …

HTLV-1 proviral load as an indicative marker of HAM/TSP: a systematic review of studies of patients with HAM/TSP

SS Bassi, R Coutinho, VN Olavarria, F Martin… - Retrovirology, 2014 - Springer
The diagnosis of HAM/TSP is based on criteria, as proposed by the World Health
Organization, revised in 1989. This primarily relies on diagnosis through laboratory criteria …

HTLV-1 proviral load in peripheral blood mononuclear cells quantified in 100 HAM/TSP patients: a marker of disease progression

S Olindo, A Lézin, P Cabre, H Merle, M Saint-Vil… - Journal of the …, 2005 - Elsevier
A high proviral load of human T cell lymphotropic virus type 1 (HTLV-1) in peripheral blood
mononuclear cells (PBMCs) has been reported in patients with HTLV-1-associated …

Digital droplet PCR (ddPCR) for the precise quantification of human T-lymphotropic virus 1 proviral loads in peripheral blood and cerebrospinal fluid of HAM/TSP …

GS Brunetto, R Massoud, EC Leibovitch… - Journal of …, 2014 - Springer
An elevated human T cell lymphotropic virus 1 (HTLV)-1 proviral load (PVL) is the main risk
factor for developing HTLV-1-associated myelopathy/tropical spastic paraparesis …

HTLV-I proviral load correlates with progression of motor disability in HAM/TSP: analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years

T Matsuzaki, M Nakagawa, M Nagai, K Usuku… - Journal of …, 2001 - Springer
To clarify clinical and laboratory findings that may be related to the pathomechanism of
HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), we analyzed these …