The role of maternal immune responses in tolerance induction is poorly understood. To
study whether maternal allergen sensitization affects offspring susceptibility to food allergy …

Allergic asthma is a chronic lung disease resulting from an inappropriate T helper (Th)-2
response to environmental antigens. Early tolerance induction is an attractive approach for …

We examined whether maternal exposure to food antigens during lactation and maternal
allergic status would affect the development of food allergy in offspring. OVA‐sensitized or …

The prevalence of food allergy has been steadily rising worldwide with the highest incidence
noted among younger children, and increasingly recognized as a growing public concern …

Allergens can be maternally transferred to the fetus or neonate, though it is uncertain how
this initial allergen exposure may impact the development of allergy responses. To evaluate …

BACKGROUND: Allergy prevention must start early because environmental exposures
during pregnancy and young life determine disease risk. OBJECTIVE: In this study we …

Allergen exclusion measures during pregnancy and lactation have been given
consideration in studies of primary allergy prevention but complete avoidance of …

Background Preconception allergen immunization prevents neonatal allergen sensitization
in mice by a complex interaction between regulatory cells/factors and antibodies. The …

Background Patients with food allergy produce high-titer IgE antibodies that bind to mast
cells through FcεRI and trigger immediate hypersensitivity reactions on antigen encounter …

Expression of Th2 immunity against environmental Ags is the hallmark of the allergic
phenotype and contrasts with the Th1-like pattern, which is stably expressed in healthy …