Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

Neurodegenerative diseases are disorders characterized by progressive loss of neurons
associated with deposition of proteins showing altered physicochemical properties in the …

Neurodegenerative diseases are characterised by selective dysfunction and progressive
loss of synapses and neurons associated with pathologically altered proteins that deposit …

Genetic factors are central to the etiology of neurodegeneration, both as monogenic causes
of heritable disease and as modifiers of susceptibility to complex, sporadic disorders. Over …

Neurodegenerative disorders are characterized by the formation of distinct pathological
changes in the brain, including extracellular protein deposits, cellular inclusions, and …

Neurodegenerative diseases are characterised by neuronal loss and cerebral deposition of
proteins with altered physicochemical properties. The major proteins are amyloid-β (Aβ), tau …

The number of neurodegenerative diseases is currently estimated to be a few hundred, and,
among these, many appear to overlap with one another clinically and pathologically …

My patients frequently ask,“Why does research take so long?”,“Why is progress so slow?”,
and “Why don't we have effective therapies for these devastating diseases?” At first thought …

Neurodegenerative diseases are a pathologically, clinically and genetically diverse group of
disorders without effective disease-modifying therapies. Pathologically, these disorders are …

The neurological diseases described in this review supplement impact across a wide
spectrum of the population. Here, their similarities and differences are highlighted, and …