The susceptibility genes in diabetic nephropathy

L Wei, Y Xiao, L Li, X Xiong, Y Han, X Zhu, L Sun - Kidney Diseases, 2018 - karger.com
Background: Diabetes mellitus (DM) poses a severe threat to global public health. Diabetic
nephropathy (DN) is one of the most common complications of diabetes and the leading …

Molecular genetic approaches for studying the etiology of diabetic nephropathy

DPK Ng, AS Krolewski - Current Molecular Medicine, 2005 - ingentaconnect.com
A critical challenge faced by clinical nephrologists today is the escalating number of patients
developing end stage renal disease, a major proportion of which is attributed to diabetic …

Genetics and epigenetics of diabetic nephropathy

R Liu, K Lee, JC He - Kidney Diseases, 2015 - karger.com
Background: Diabetic nephropathy (DN) is the most common cause of end-stage renal
disease (ESRD) in the USA and worldwide, contributing to significant morbidity and mortality …

The prevalence and management of diabetic nephropathy in Asia

Y Tomino, T Gohda - Kidney Diseases, 2015 - karger.com
Abstract Background: Diabetic nephropathy (DN), especially type 2 diabetes, is now
increasing rapidly worldwide, also in Asian countries, and is one of the major long-term …

Genetics of diabetic nephropathy

S Maeda - Therapeutic Advances in Cardiovascular Disease, 2008 - journals.sagepub.com
Genetic susceptibility has been proposed as an important factor for the development and
progression of diabetic nephropathy, and research efforts have been invested worldwide to …

Genetics of diabetic nephropathy: a long road of discovery

AJ McKnight, S Duffy, AP Maxwell - Current Diabetes Reports, 2015 - Springer
The global prevalence of diabetic nephropathy is rising in parallel with the increasing
incidence of diabetes in most countries. Unfortunately, up to 40% of persons diagnosed with …

The genetics of diabetic nephropathy

E Brennan, C McEvoy, D Sadlier, C Godson, F Martin - Genes, 2013 - mdpi.com
Up to 40% of patients with type 1 and type 2 diabetes will develop diabetic nephropathy
(DN), resulting in chronic kidney disease and potential organ failure. There is evidence for a …

Genetics of diabetic nephropathy: are there clues to the understanding of common kidney diseases?

BR Conway, AP Maxwell - Nephron Clinical practice, 2009 - karger.com
Diabetic nephropathy is the most common cause of end-stage renal disease in the Western
world. There is evidence for a genetic susceptibility to diabetic kidney disease, but despite …

New susceptibility loci associated with kidney disease in type 1 diabetes

N Sandholm, RM Salem, AJ McKnight, EP Brennan… - 2012 - journals.plos.org
Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes
and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or …

Insights into the genetic architecture of diabetic nephropathy

ND Palmer, BI Freedman - Current diabetes reports, 2012 - Springer
Diabetic nephropathy (DN) is a devastating complication of type 1 and type 2 diabetes and
leads to increased morbidity and premature mortality. Susceptibility to DN has an inherent …