Effect of fluorinert on the histological properties of formalin-fixed human brain tissue

JE Iglesias, S Crampsie, C Strand… - … of Neuropathology & …, 2018 - academic.oup.com
Fluorinert (perfluorocarbon) represents an inexpensive option for minimizing susceptibility
artifacts in ex vivo brain MRI scanning, and provides an alternative to Fomblin. However, its …

Formalin fixed brains are useful for magnetic resonance imaging (MRI) study

H Nagara, T Inoue, T Koga, T Kitaguchi… - Journal of the …, 1987 - Elsevier
We carried out magnetic resonance imaging (MRI) studies on human brains which had been
fixed in formalin solution for over 2 years and had been proven neuropathologically to be …

MRI artifacts in human brain tissue after prolonged formalin storage

S van Duijn, RJA Nabuurs… - Magnetic resonance …, 2011 - Wiley Online Library
For the interpretation of magnetic resonance imaging (MRI) abnormalities in brain
pathology, often ex vivo tissue is used. The purpose of this study was to determine the …

Optimization of sample preparation for MRI of formaldehyde-fixed brains

Y Leprince, B Schmitt, É Chaillou… - 23rd annual meeting …, 2015 - cea.hal.science
Magnetic resonance imaging of post-mortem brains allows long acquisition times up to
several days and can be used to obtain high-resolution images at high field (7 T) which can …

19F magnetic resonance imaging and spectroscopy of a fluorinated neuroleptic ligand: In vivo and in vitro studies

DC Arndt, AV Ratner, KF Faull, JD Barchas… - Psychiatry research, 1988 - Elsevier
The bulk biodistribution of a trifluorinated neuroleptic (fluphenazine) was studied using 19 F
magnetic resonance imaging (MRI). Fifteen male Sprague-Dawley rats were injected with …

[HTML][HTML] From fix to fit into the autoptic human brains

B Paradiso, M Simonato, G Thiene… - European journal of …, 2018 - ncbi.nlm.nih.gov
Formalin-fixed, paraffin embedded (FFPE) human brain tissues are very often stored in
formalin for long time. Formalin fixation reduces immunostaining, and the DNA/RNA …

In vivo fluorine‐19 MR imaging: relaxation enhancement with Gd‐DTPA

H Lee, RR Price, GE Holburn… - Journal of Magnetic …, 1994 - Wiley Online Library
The lack of a naturally occurring background signal from fluorine in magnetic resonance
(MR) imaging makes fluorinated compounds potentially attractive candidates for tissue …

Comparison of histological procedures and antigenicity of human post-mortem brains fixed with solutions used in gross anatomy laboratories

EM Frigon, A Gérin-Lajoie, M Dadar, D Boire… - Frontiers in …, 2024 - frontiersin.org
Background Brain banks provide small tissue samples to researchers, while gross anatomy
laboratories could provide larger samples, including complete brains to neuroscientists …

Fluorine (19F) MRS and MRI in biomedicine

J Ruiz‐Cabello, BP Barnett, PA Bottomley… - NMR in …, 2011 - Wiley Online Library
Shortly after the introduction of 1H MRI, fluorinated molecules were tested as MR‐detectable
tracers or contrast agents. Many fluorinated compounds, which are nontoxic and chemically …

MR microscopy of formalin fixed paraffin embedded histology specimens

S Macura, PK Mishra, JD Gamez… - Magnetic resonance in …, 2014 - Wiley Online Library
Purpose Archived formalin‐fixed paraffin‐embedded (FFPE) tissue collections represent a
valuable informational resource for numerous studies. However, there is no NMR signal …