Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome
Despite a growing body of evidence, the role of the gut microbiome in cardiovascular
diseases is still unclear. Here, we present a systems-genome-wide and metagenome-wide …
diseases is still unclear. Here, we present a systems-genome-wide and metagenome-wide …
Population study of the gut microbiome: associations with diet, lifestyle, and cardiometabolic disease
Background The human gut harbors trillions of microbes that play dynamic roles in health.
While the microbiome contributes to many cardiometabolic traits by modulating host …
While the microbiome contributes to many cardiometabolic traits by modulating host …
The gut microbiome in atherosclerotic cardiovascular disease
The gut microbiota has been linked to cardiovascular diseases. However, the composition
and functional capacity of the gut microbiome in relation to cardiovascular diseases have not …
and functional capacity of the gut microbiome in relation to cardiovascular diseases have not …
Gut microbiome associations with host genotype vary across ethnicities and potentially influence cardiometabolic traits
U Boulund, DM Bastos, B Ferwerda, BJ van den Born… - Cell host & …, 2022 - cell.com
Previous studies in mainly European populations have reported that the gut microbiome
composition is associated with the human genome. However, the genotype-microbiome …
composition is associated with the human genome. However, the genotype-microbiome …
The gut microbiome contributes to a substantial proportion of the variation in blood lipids
Rationale: Evidence suggests that the gut microbiome is involved in the development of
cardiovascular disease, with the host–microbe interaction regulating immune and metabolic …
cardiovascular disease, with the host–microbe interaction regulating immune and metabolic …
Gut microbial associations to plasma metabolites linked to cardiovascular phenotypes and risk: a cross-sectional study
A Kurilshikov, ICL van den Munckhof, L Chen… - Circulation …, 2019 - Am Heart Assoc
Rationale: Altered gut microbial composition has been linked to cardiovascular diseases
(CVDs), but its functional links to host metabolism and immunity in relation to CVD …
(CVDs), but its functional links to host metabolism and immunity in relation to CVD …
Host genetic variation impacts microbiome composition across human body sites
R Blekhman, JK Goodrich, K Huang, Q Sun… - Genome biology, 2015 - Springer
Background The composition of bacteria in and on the human body varies widely across
human individuals, and has been associated with multiple health conditions. While microbial …
human individuals, and has been associated with multiple health conditions. While microbial …
Gut microbiota composition and blood pressure: the CARDIA study
Animal models support a role for the gut microbiota in the development of hypertension.
There has been a lack of epidemiological cohort studies to confirm these findings in human …
There has been a lack of epidemiological cohort studies to confirm these findings in human …
Unraveling the environmental and genetic interactions in atherosclerosis: central role of the gut microbiota
E Org, M Mehrabian, AJ Lusis - Atherosclerosis, 2015 - Elsevier
Recent studies have convincingly linked gut microbiota to traits relevant to atherosclerosis,
such as insulin resistance, dyslipidemia and inflammation, and have revealed novel disease …
such as insulin resistance, dyslipidemia and inflammation, and have revealed novel disease …
Causal associations between gut microbiome and cardiovascular disease: a Mendelian randomization study
Y Zhang, X Zhang, D Chen, J Lu, Q Gong… - Frontiers in …, 2022 - frontiersin.org
Background Observational studies have shown gut microbiomes were associated with
cardiovascular diseases (CVDs), but their roles remain controversial, and these associations …
cardiovascular diseases (CVDs), but their roles remain controversial, and these associations …