Vitamin D, DNA methylation, and breast cancer

KM O'Brien, DP Sandler, Z Xu, HK Kinyamu… - Breast Cancer …, 2018 - Springer
Background Vitamin D has anticarcinogenic and immune-related properties and may protect
against some diseases, including breast cancer. Vitamin D affects gene transcription and …

Genetic polymorphisms in vitamin D metabolism and signaling genes and risk of breast cancer: a nested case-control study

TV Clendenen, W Ge, KL Koenig, T Axelsson, M Liu… - PLoS …, 2015 - journals.plos.org
Genetic polymorphisms in vitamin D metabolism and signaling genes have been
inconsistently associated with risk of breast cancer, though few studies have examined …

Single-Nucleotide Polymorphisms in Vitamin D–Related Genes May Modify Vitamin D–Breast Cancer Associations

KM O'Brien, DP Sandler, HK Kinyamu, JA Taylor… - … Biomarkers & Prevention, 2017 - AACR
Background: We previously observed that high serum 25-hydroxyvitamin D (25 (OH) D;>
38.0 ng/mL) was inversely associated with breast cancer. Here, we examined effect …

Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer risk

S Abbas, A Nieters, J Linseisen, T Slanger… - Breast Cancer …, 2008 - Springer
Abstract Introduction Vitamin D receptor (VDR) genotypes may influence breast cancer risk
by altering potential anticarcinogenic effects of vitamin D, but epidemiological studies have …

The Gc2 Allele of the Vitamin D Binding Protein Is Associated with a Decreased Postmenopausal Breast Cancer Risk, Independent of the Vitamin D Status

S Abbas, J Linseisen, T Slanger, S Kropp… - … Biomarkers & Prevention, 2008 - AACR
Vitamin D pathway gene polymorphisms may influence breast cancer risk by altering
potential anticarcinogenic effects of vitamin D. The association between polymorphisms in …

Vitamin D-related gene polymorphisms, plasma 25-hydroxyvitamin D, and breast cancer risk

LL Reimers, KD Crew, PT Bradshaw, RM Santella… - Cancer causes & …, 2015 - Springer
Purpose Studies of vitamin D-pathway genetic variants in relation to cancer risk have been
inconsistent. We examined the associations between vitamin D-related genetic …

Vitamin D–Associated Genetic Variation and Risk of Breast Cancer in the Breast and Prostate Cancer Cohort Consortium (BPC3)

AM Mondul, IM Shui, K Yu, SJ Weinstein… - … Biomarkers & Prevention, 2015 - AACR
Background: Two recent genome-wide association studies (GWAS) identified SNPs in or
near four genes related to circulating 25-hydroxyvitamin D [25 (OH) D] concentration. To …

Serum 25-hydroxyvitamin D concentrations and postmenopausal breast cancer risk: a nested case control study in the Cancer Prevention Study-II Nutrition Cohort

ML McCullough, VL Stevens, R Patel, EJ Jacobs… - Breast cancer …, 2009 - Springer
Introduction Vitamin D status measured during adulthood has been inversely associated
with breast cancer risk in some, but not all, studies. Vitamin D has been hypothesized to …

Common genetic variants in the vitamin D pathway including genome-wide associated variants are not associated with breast cancer risk among Chinese women

T Dorjgochoo, R Delahanty, W Lu, J Long, Q Cai… - … , biomarkers & prevention, 2011 - AACR
Background: Previous studies evaluating the association of vitamin D–related genetic
variants with breast cancer risk have produced inconsistent results. Methods: We evaluated …

Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case-control study

ML McCullough, VL Stevens, WR Diver… - Breast Cancer …, 2007 - Springer
Abstract Introduction Vitamin D receptor (VDR) polymorphisms have been inconsistently
associated with breast cancer risk. Whether risk is influenced by polymorphisms in other …