During viral entry, enveloped viruses require the fusion of their lipid envelope with host cell
membranes. For coronaviruses, this critical step is governed by the virally-encoded spike (S) …

Coronavirus-cell entry programs involve virus-cell membrane fusions mediated by viral
spike (S) proteins. Coronavirus S proteins acquire membrane fusion competence by …

The S2 domain of the coronavirus spike (S) protein is known to be responsible for mediating
membrane fusion. In addition to a well-recognized cleavage site at the S1–S2 boundary, a …

Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is a rapidly
emerging pathogen with potentially serious consequences for public health. Here we …

The spike protein (S) of severe acute respiratory syndrome coronavirus (SARS-CoV) is
responsible for receptor binding and membrane fusion. It contains a highly conserved …

The coronavirus spike protein (S) plays a key role in the early steps of viral infection, with the
S1 domain responsible for receptor binding and the S2 domain mediating membrane fusion …

Many viral fusion proteins are primed by proteolytic cleavage near their fusion peptides.
While the coronavirus (CoV) spike (S) protein is known to be cleaved at the S1/S2 boundary …

The coronavirus spike protein is a multifunctional molecular machine that mediates
coronavirus entry into host cells. It first binds to a receptor on the host cell surface through its …

Coronaviruses are enveloped positive-stranded RNA viruses that replicate in the cytoplasm.
To deliver their nucleocapsid into the host cell, they rely on the fusion of their envelope with …

Enveloped viruses enter cells by viral glycoprotein-mediated binding to host cells and
subsequent fusion of virus and host cell membranes. For the coronaviruses, viral spike (S) …