免疫检查点抑制剂治疗结直肠癌生物标志物的研究进展
黄铭琪, 张涛, 李龙浩 - 中国肿瘤临床, 2019 - cjco.cn
免疫检查点抑制剂(immune checkpoint inhibitors, ICI) 在多种晚期实体瘤治疗中取得了较好的
临床疗效, 其中包括结直肠癌. 但是大多数的肿瘤患者对ICI 的客观反应率(objective response …
临床疗效, 其中包括结直肠癌. 但是大多数的肿瘤患者对ICI 的客观反应率(objective response …
Prognostic value of programed cell death-1 ligand expression in colorectal cancer and its correlation with cytotoxic tumor-infiltrating lymphocytes
GE Esheba - The Egyptian Journal of Hospital Medicine, 2019 - ejhm.journals.ekb.eg
Background: colorectal cancer (CRC) is a major cause of cancer-related death worldwide. In
recent years, targeting the programed cell death (PD-1)/programed cell death-1 ligand (PD …
recent years, targeting the programed cell death (PD-1)/programed cell death-1 ligand (PD …
Prognostic significance of PD-L1 expression in patients with colorectal cancer: a meta-analysis
S Liu, R Ma, H Cao, D Chen, C Jing… - Oncology and …, 2019 - journals.lww.com
Background The association between the expression of programmed cell death 1 (PD-1) or
its ligand [programmed cell death ligand-1 (PD-L1)] and colorectal cancer (CRC) survival …
its ligand [programmed cell death ligand-1 (PD-L1)] and colorectal cancer (CRC) survival …
[PDF][PDF] IL6 modulates the immune status of the tumor microenvironment to facilitate
AT Tanino - researchgate.net
It is unknown as to how liver metastases are correlated with host immune status in colorectal
cancer. In this study, we found that IL6, a proinflammatory cytokine produced in tumor …
cancer. In this study, we found that IL6, a proinflammatory cytokine produced in tumor …
Developments and emerging trends in PD-L1 research in gastrointestinal cancers (2000-2018): a bibliometric perspective
G Jiang, X Zhang, H Liu, X Lv, F Wei, T Yu, X Cai - 2019 - researchsquare.com
Background: The programmed death-ligand 1 (PD-L1) pathway inhibits T-cell receptor-
mediated production of IL-2 and T-cell proliferation and plays an important role in the …
mediated production of IL-2 and T-cell proliferation and plays an important role in the …
Untersuchungen zu den kostimulatorischen Signalwegen PD-1/PD-L1 und CD137/CD137L beim kolorektalen Karzinom
M Wagner - 2019 - opus.bibliothek.uni-wuerzburg.de
Kostimulatorische Signalwege spielen beim Zustandekommen einer T-Zell-gebundenen
Effektor-Immunantwort eine entscheidende Rolle. In dieser Arbeit wurde die Expression der …
Effektor-Immunantwort eine entscheidende Rolle. In dieser Arbeit wurde die Expression der …
Immunological Treatment in Gastrointestinal Cancers
HR Callata-Carhuapoma… - Textbook of …, 2019 - Springer
Colorectal cancer is a common malignancy around the world, with an important mortality
rate among other malignancies. The cornerstone of treatment is curative surgery as 40% of …
rate among other malignancies. The cornerstone of treatment is curative surgery as 40% of …
The immune microenvironment of colorectal cancer-Relationship with survival, sidedness, and pre-diagnostic anthropometry
J Berntsson - 2019 - portal.research.lu.se
Colorectal cancer (CRC) is the third most common cancer worldwide. Increasing evidence
suggests that CRC should be considered a heterogeneous disease, with multiple …
suggests that CRC should be considered a heterogeneous disease, with multiple …
[PDF][PDF] Prognostic Utility of CDX2 and PD-L1 in Rectal Cancer
E Paver, B Nguyen, M Fadia, S Ali - researchgate.net
To the Editor: In current practice, the only definitive indication for neoadjuvant treatment for
locally advanced rectal adenocarcinoma remains to be the presence of T3/T4 tumor …
locally advanced rectal adenocarcinoma remains to be the presence of T3/T4 tumor …
Influence of KRAS activation in the colorectal cancer immunosurveillance escape
ALMC Machado - 2019 - recipp.ipp.pt
The immune system as a host defense system watches the cell growth and division,
eliminating cells with antigens different from those present in healthy cells. However, some …
eliminating cells with antigens different from those present in healthy cells. However, some …