[HTML][HTML] Ph 染色体样急性淋巴细胞白血病的研究进展

吴玉玲, 向兵, 刘霆 - Chinese Journal of Hematology, 2019 - ncbi.nlm.nih.gov
急性淋巴细胞白血病(ALL) 是前体淋巴细胞发生克隆性异常增殖所致的恶性疾病, 近年来,
随着分子生物学基因组测序技术的进步, 在儿童和成人ALL 患者中发现了一个高危的B-ALL …

Research progress in Ph-like acute lymphoblastic leukemia

YL Wu, B Xiang, T Liu - Zhonghua xue ye xue za zhi= Zhonghua …, 2019 - europepmc.org
急性淋巴细胞白血病 (ALL) 是前体淋巴细胞发生克隆性异常增殖所致的恶性疾病, 近年来,
随着分子生物学基因组测序技术的进步, 在儿童和成人 ALL 患者中发现了一个高危的 B-ALL …

Identification of new therapeutic targets in CRLF2-overexpressing B-ALL through discovery of TF-gene regulatory interactions

S Badri, B Carella, P Lhoumaud, DM Castro, CS Gibbs… - bioRxiv, 2019 - biorxiv.org
Although genetic alterations are initial drivers of disease, aberrantly activated transcriptional
regulatory programs are often responsible for the maintenance and progression of cancer …

[HTML][HTML] Signaling input from divergent pathways subverts malignant B-cell transformation

LN Chan, MA Murakami, R Caesar, C Hurtz, K Kume… - Blood, 2019 - Elsevier
Background and significance: Normal B-cells constantly exchange information with their
environment and depend on external cues for proliferation and survival that engage multiple …

Opredelitev delecij gena IKZF1 pri otrocih z B-celično akutno limfoblastno levkemijo

G Marinšek - 2019 - repozitorij.uni-lj.si
Akutna limfoblastna levkemija (ALL), za katero je značilna maligna transformacija predniških
celic B ali T limfocitov, je najpogostejša rakava bolezen pri otrocih. Sodobni načini …

[PDF][PDF] A B-cell acute lymphoblastic leukemia regulatory network defines novel therapeutic targets in IGH-CRLF2 patients

S Badri, B Carella, P Lhoumaud, DM Castro… - bioRxiv, 2019 - scholar.archive.org
A B-cell acute lymphoblastic leukemia regulatory network defines novel therapeutic targets in
IGH-CRLF2 patients Page 1 1 A B-cell acute lymphoblastic leukemia regulatory network defines …

[PDF][PDF] 5. Newer approaches towards theranostics in Acute Lymphoblastic Leukemia

GU Raval - Guidelines for the Management for Clinical Genomics …, 2019 - tmc.gov.in
Hematopoietic stem cells are an important source of different lymphocytes which essentially
forms the basis of our immune system. The lymphoid malignancies include tumors of cells …

Interrogating the Mechanistic Basis for Cytokine-Mediated Glucocorticoid Resistance in Lymphoid-Driven Diseases

LK Meyer - 2019 - escholarship.org
Glucocorticoids (GCs) are potently immunosuppressive due to their pro-apoptotic effects on
lymphoid cells, leading to their utility in a wide range of clinical contexts including …

[PDF][PDF] Methotrexat-assoziierte Toxizität bei Kindern mit akuter lymphoblastischer Leukämie und Down Syndrom

M Kroll - 2019 - macau.uni-kiel.de
Kinder mit Down Syndrom (DS) haben ein erhöhtes Risiko an einer akuten
lymphoblastischen Leukämie (ALL) zu erkranken (DS-ALL) und stellen einen Anteil von bis …

[引用][C] BCR-ABL1–like B-Acute Lymphoblastic Leukemia/Lymphoma