Urinary antibacterial activity of fosfomycin and nitrofurantoin at registered dosages in healthy volunteers

RA Wijma, A Huttner, S van Dun, W Kloezen… - International journal of …, 2019 - Elsevier
Given emerging uropathogen resistance to more recent antibiotics, old antibiotics used for
uncomplicated urinary tract infection (UTI) warrant re-examination. In this study, the urinary …

Fundamental study of behaviors of in-source collision induced dissociation and shifting the linear range of calibration curves of various drugs and the metabolites …

M MAEKAWA, T TSUKAMOTO, S TAKASAKI… - …, 2019 - jstage.jst.go.jp
Therapeutic drug monitoring (TDM) is a clinical practice that designs personalized
medication for patients with blood concentrations of the drug. TDM approach is used for …

Insufficient harmonization of antibiotics assays–Polish experience with an external quality assessment program in the years 2011–2018

R Kowalski, A Ćwiklińska, M Lizakowski… - Clinical …, 2019 - Elsevier
Introduction Treatment with vancomycin and gentamycin requires strict monitoring of its
serum concentration for proper dosage optimization. This study aimed to assess the quality …

Prevention of drug-related complications in cystic fibrosis

R van der Meer, DJ Touw… - Current Opinion in …, 2019 - journals.lww.com
With increased life expectancy which is, in part, because of better treatment options, the
burden of pharmacotherapy in cystic fibrosis patients will increase. This has a high impact …

Microdialysis combined with liquid chromatography-tandem mass spectrometry for the quantitation of gemifloxacin and its application to a muscle penetration study in …

R Zhao, Q Wang, XX Hu, TY Nie, XY Yang, CR Li, X Lu… - Plos one, 2019 - journals.plos.org
Pharmacological efficacy is based on the drug concentration in target tissues, which usually
cannot be represented by the plasma concentration. The purpose of this study was to …

Evaluation of aminoglycosides utilization in intensive care units of a teaching hospital in southern Iran

A Vazin, M Mirjalili, S Asadi - Pharmacy Practice (Granada), 2019 - SciELO Espana
Resumen VAZIN, Afsaneh; MIRJALILI, Mahtabalsadat y ASADI, Sara. Evaluation of
aminoglycosides utilization in intensive care units of a teaching hospital in southern Iran …

Development and validation of analytical methods for therapeutic drug monitoring

M Pingeon - 2019 - elea.unisa.it
The US Food and Drug Administration defines as Precision or Personalized Medicine (PM)
an innovative therapeutic approach that tailors therapy and prevention on patients based on …

[PDF][PDF] Dottorato di Ricerca in Medicina Traslazionale dello Sviluppo e dell'Invecchiamento Attivo XXXI ciclo

M Pingeon - core.ac.uk
Riassunto La US Food and Drug Administration definisce con il termine Medicina di
Precisione o Personalizzata (MP) un approccio terapeutico innovativo che identifica …

Therapeutic drug monitoring for beta-lactams and colistin: is it ready for prime time?

A Sunavala, U Agrawal, P VGala - Critical Care Update, 2019 - books.google.com
In the year 2018, the management of sepsis in India faces several significant hurdles, of
which extreme drug resistance (XDR) among gram-negative (GN) pathogens is undoubtedly …

Individualization of drug therapy considering pharmacokinetic and clinical factors

MR Munz - 2019 - opus.bibliothek.uni-wuerzburg.de
In the „Position Paper of the Division of Clinical Pharmacy of the German Pharmaceutical
Society (DPhG)” clinical pharmacy is defined as the science and practice of the rational use …