Pharynx–larynx cancer is a complex malignant tumor with the sixth-highest morbidity and
mortality rate worldwide. The telomerase reverse transcriptase TERT-CLPTM1L gene …

DNase I‑hypersensitive sites (DHSs) serve key roles in the regulation of gene transcription
as markers of cis‑regulatory elements (CREs). Recent advances in next‑generation …

Deciphering the shared genetic basis of distinct cancers has the potential to elucidate
carcinogenic mechanisms and inform broadly applicable risk assessment efforts. However …

Genome-wide association studies (GWAS) have identified∼ 20 melanoma susceptibility
loci. To identify susceptibility genes and variants simultaneously from multiple GWAS loci …

Background: A previous genome-wide association study showed that hTERT rs10069690
and rs2736100 polymorphisms were associated with thyroid cancer risk. Objective: This …

Anal squamous intraepithelial lesions (ASIL) or anal intraepithelial neoplasia (AIN) are
precancerous lesions. microRNAs (miRNAs) have been implicated in cervical …

Background: Numerous studies have evaluated the relationship between the human
telomerase reverse transcriptase (TERT) gene variant rs2736098 polymorphism and …

AbstractBackground: Telomere length and telomerase activity are crucial for cancer initiation
and the survival of tumors. Tel-omere length is maintained by telomerase in 90% of human …

Genome-wide association studies (GWAS) have found hundreds of single nucleotide
polymorphisms (SNPs) associated with increased risk of cancer. However, the amount of …

Background: A large number of studies have been conducted to investigate relationships
between genetic variants and risk of esophageal cancer in the past several decades …