Genome-wide copy number variation-, validation-and screening study implicates a novel copy number polymorphism associated with suicide attempts in major …

S Rao, M Shi, X Han, MHB Lam, G Liu, YK Wing… - bioRxiv, 2019 - biorxiv.org
Background The genetic basis of suicide attempts (SA) remained unclear, especially for the
copy number variations (CNVs) involved. The present study aimed to identify the …

Genome-wide copy number variation-, validation-and screening study implicates a new copy number polymorphism associated with suicide attempts in major …

S Rao, M Shi, X Han, MHB Lam, WT Chien, K Zhou… - Gene, 2020 - Elsevier
Background The genetic basis of suicide attempts (SA) remains unclear. Especially the role
of copy number variations (CNVs) remains to be elucidated. The present study aimed to …

[HTML][HTML] Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

N Mullins, TB Bigdeli, AD Børglum… - The American journal …, 2019 - ncbi.nlm.nih.gov
Objective: Over 90% of suicide attempters have a psychiatric diagnosis, however twin and
family studies suggest that the genetic etiology of suicide attempt (SA) is partially distinct …

[HTML][HTML] Copy number variation in subjects with major depressive disorder who attempted suicide

RH Perlis, D Ruderfer, SP Hamilton, C Ernst - 2012 - journals.plos.org
Background Suicide is one of the top ten leading causes of death in North America and
represents a major public health burden, partcularly for people with Major Depressive …

[HTML][HTML] Genomewide association scan of suicidal thoughts and behaviour in major depression

A Schosser, AW Butler, M Ising, N Perroud, R Uher… - PloS one, 2011 - journals.plos.org
Background Suicidal behaviour can be conceptualised as a continuum from suicidal
ideation, to suicidal attempts to completed suicide. In this study we identify genes …

Genetic correlations between suicide attempts and psychiatric and intermediate phenotypes adjusting for mental disorders

D Fujikane, K Ohi, A Kuramitsu, K Takai… - Psychological …, 2024 - cambridge.org
BackgroundSuicide attempts are a moderately heritable trait, and genetic correlations with
psychiatric and related intermediate phenotypes have been reported. However, as several …

[HTML][HTML] Genetic associations with suicide attempt severity and genetic overlap with major depression

DF Levey, R Polimanti, Z Cheng, H Zhou… - Translational …, 2019 - nature.com
Abstract In 2015,~ 800,000 people died by suicide worldwide. For every death by suicide
there are as many as 25 suicide attempts, which can result in serious injury even when not …

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genomewide association and polygenic scoring study

N Mullins, N Perroud, R Uher, AW Butler… - American Journal of …, 2014 - Wiley Online Library
Epidemiological studies have recognized a genetic diathesis for suicidal behavior, which is
independent of other psychiatric disorders. Genomewide association studies (GWAS) on …

GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

N Mullins, TB Bigdeli, AD Børglum… - American journal of …, 2019 - Am Psychiatric Assoc
Objective: More than 90% of people who attempt suicide have a psychiatric diagnosis;
however, twin and family studies suggest that the genetic etiology of suicide attempt is …

[HTML][HTML] Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study

A Erlangsen, V Appadurai, Y Wang, G Turecki… - Molecular …, 2020 - nature.com
Family studies have shown an aggregation of suicidal behavior in families. Yet, molecular
studies are needed to identify loci accounting for genetic heritability. We conducted a …