After the great expansion of genome-wide association studies, their scientific methodology
and, notably, their data analysis has matured in recent years, and they are a keystone in …

With the advent of genome-wide association (GWA) studies, researchers are hoping that
reliable genetic association of common human complex diseases/traits can be detected …

Phenome-wide association studies (PheWAS) have been used to replicate known genetic
associations and discover new phenotype associations for genetic variants. This PheWAS …

Nextgeneration sequencing has enabled the study of a comprehensive catalogue of
genetic variants for their impact on various complex diseases. Numerous consortia studies …

Results from genome-wide association studies (GWAS) can be used to infer causal
relationships between phenotypes, using a strategy known as 2-sample Mendelian …

This review article describes the background and practical aspects for the Genome Wide
Association Studies (GWAS). I introduce several softwares which are actually used in …

Results from genome-wide association studies (GWAS) can be used to infer causal
relationships between phenotypes, using a strategy known as 2-sample Mendelian …

Background: Pathway analysis is widely used in omics studies. Pathway-based data
integration and visualization is a critical component of the analysis. To address this need, we …

Genome-wide association studies (GWASs) have identified thousands of genetic loci
associated with complex traits, including a wide variety of diseases. Despite the successful …

As highlighted in a recent editorial in the Journal (Am J Epidemiol. 2014; 180 (2): 127–128),
the research area of “-omics” includes genomics, proteomics, metabolomics, and nascent …