Molecular basis and cellular mechanisms of eosinophilic esophagitis for the clinical practice

Á Arias, AJ Lucendo - Expert Review of Gastroenterology & …, 2019 - Taylor & Francis
ABSTRACT Introduction: Eosinophilic esophagitis (EoE) is a chronic, allergen-driven
inflammatory esophageal disease characterized by predominantly eosinophilic inflammation …

Cellular and molecular immunological mechanisms in eosinophilic esophagitis: an updated overview of their clinical implications

AJ Lucendo - Expert review of gastroenterology & hepatology, 2014 - Taylor & Francis
Eosinophilic esophagitis (EoE) is a pathophysiologically complex disorder driven by distinct,
multiple mechanisms involving a large number of cells, molecules, and genes. Associated …

Epithelial origin of eosinophilic esophagitis

M Rochman, NP Azouz, ME Rothenberg - Journal of Allergy and Clinical …, 2018 - Elsevier
Eosinophilic esophagitis (EoE) is a chronic, allergen-driven inflammatory disease of the
esophagus characterized predominantly by eosinophilic inflammation, leading to …

Biology and treatment of eosinophilic esophagitis

ME Rothenberg - Gastroenterology, 2009 - Elsevier
Eosinophilic esophagitis is a recently recognized but expanding disorder characterized by
antigen-driven eosinophil accumulation in the esophagus. Symptoms frequently mimic those …

[HTML][HTML] Mechanistic insights into eosinophilic esophagitis: therapies targeting pathophysiological mechanisms

S Massironi, G Mulinacci, C Gallo, A Elvevi, S Danese… - Cells, 2023 - mdpi.com
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease characterized by
eosinophilic infiltration of the esophagus. It arises from a complex interplay of genetic …

Do we know what causes eosinophilic esophagitis? A mechanistic update

TM Runge, ES Dellon - Current gastroenterology reports, 2015 - Springer
The mechanisms underlying eosinophilic esophagitis (EoE) have been intensely
investigated, and significant advances have been made in understanding the pathogenesis …

Eosinophilic esophagitis: Immune mechanisms and therapeutic targets

D Khokhar, S Marella, G Idelman… - Clinical & …, 2022 - Wiley Online Library
Eosinophilic esophagitis (EoE) is an emerging chronic inflammatory disease of the
oesophagus and is clinically characterized by upper gastrointestinal (GI) symptoms …

Mechanisms of disease of eosinophilic esophagitis

BP Davis, ME Rothenberg - Annual Review of Pathology …, 2016 - annualreviews.org
Eosinophilic esophagitis (EoE) is a recently recognized inflammatory disease of the
esophagus with clinical symptoms derived from esophageal dysfunction. The etiology of …

Breaking down the complex pathophysiology of eosinophilic esophagitis

B Underwood, TD Troutman, JT Schwartz - Annals of Allergy, Asthma & …, 2023 - Elsevier
Eosinophilic esophagitis (EoE) is a chronic and progressive immune-mediated disease of
the esophagus associated with antigen-driven type 2 inflammation and symptoms of …

[HTML][HTML] Type 2 inflammation in eosinophilic esophagitis: from pathophysiology to therapeutic targets

F Racca, G Pellegatta, G Cataldo, E Vespa… - Frontiers in …, 2022 - frontiersin.org
Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus
characterized clinically by symptoms related to esophageal dysfunction and histologically by …