The aim of this study was to apply a quality by design (QbD) approach for the development
of budesonide (BUD)-loaded large porous microparticles (LPPs) for inhalation purpose. An …

Large porous particles (LPPs) are well-known vehicles for drug delivery to the lungs.
However, it remains uncertain whether or to which extent the in vitro drug release behavior …

Sustained drug delivery is considered as an effective strategy to improve the treatment of
local lung diseases. In this context, inhalation administration of large porous microparticles …

The aim of this study is to prepare a nanosuspension of budesonide for respiratory delivery
using nebuliser by optimising its particle size and characterising its in vitro deposition …

The purpose of this research was to generate, characterize, and investigate the in vivo
efficacy of budesonide (BUD) microparticles prepared by spray-drying technology with a …

The aim of this study was to investigate the application of a spray-drying process for the
production of nanoporous microparticles (NPMPs) to budesonide, and to characterise the …

Co-suspension drug-loading technology, namely Aerosphere™, can improve fine particle
fraction (FPF) and delivered dose content uniformity (DDCU). However, because of its poor …

Drug particle physical properties are critical for the efficiency of a drug delivered to the lung.
Budesonide, as one of the inhaled glucocorticosteroids, is widely used in the treatment of …

The potential of micron-sized amorphous mesoporous silica particles as a novel controlled
release drug delivery system for pulmonary administration has been investigated …

Budesonide is a poorly water soluble corticosteroid used in the treatment of asthma and
chronic obstructive pulmonary disease (COPD). The aim of the present study was to develop …