Purpose This study aimed to detect the association between nitric oxide synthase 3 (NOS3)
gene polymorphisms (rs1799983 and rs3918181) and the susceptibility to osteonecrosis of …

Purpose Nitric oxide (NO) synthesised by endothelial NO synthase (eNOS) is a potent
regulator of internal haemodynamics. A polymorphism in intron 4 of the eNOS is associated …

Genetic polymorphism of nitric oxide synthase (NOS) can cause reduction of nitric oxide
(NO) levels and may be associated with osteonecrosis of the femoral head (ONFH) …

Background Genetic polymorphisms play a crucial role in the development of osteonecrosis
of the femoral head (ONFH). This study mainly explored the association of IL-6 variants and …

Purpose: Osteonecrosis of the femoral head (ONFH) is a disease in which cell death in the
bone occurs. This study investigated the association the tagging SNPs (tSNPs) genetic …

Objectives Necrosis of femoral head is a severe pathological state with multiple etiologies.
This study investigated the association of the 27-bp repeat polymorphism in intron 4 and …

Aim Osteonecrosis of the femoral head (ONFH) refers to bony changes caused by osteocyte
death under the effects of complicated factors, which is caused by genetic factors and certain …

A non-union, especially atrophic non-unions, is a permanent failure of healing following a
fracture and can be difficult to treat. Approximately 5–10% of fractures will result in a non …

The progressive neurodegenerative process in osteonecrosis of the femoral head (ONFH) is
accompanied by chronic inflammation, including activation of microglia and astrocytes that …

Purpose Nitric oxide (NO), a short-lived gaseous free radical, is a potent mediator of
biological responses involved in the pathogenesis of autoimmune rheumatic diseases, such …