Oncolytic virus therapy in Japan: progress in clinical trials and future perspectives

S Taguchi, H Fukuhara, T Todo - Japanese Journal of Clinical …, 2019 - academic.oup.com
Oncolytic virus therapy is a promising new option for cancer. It utilizes genetically
engineered or naturally occurring viruses that selectively replicate in and kill cancer cells …

Oncolytic virus therapy: A new era of cancer treatment at dawn

H Fukuhara, Y Ino, T Todo - Cancer science, 2016 - Wiley Online Library
Oncolytic virus therapy is perhaps the next major breakthrough in cancer treatment following
the success in immunotherapy using immune checkpoint inhibitors. Oncolytic viruses are …

Therapy with oncolytic viruses: progress and challenges

SZ Shalhout, DM Miller, KS Emerick… - Nature reviews Clinical …, 2023 - nature.com
Oncolytic viruses (OVs) are an emerging class of cancer therapeutics that offer the benefits
of selective replication in tumour cells, delivery of multiple eukaryotic transgene payloads …

[HTML][HTML] Oncolytic virotherapy, updates and future directions

C Fountzilas, S Patel, D Mahalingam - Oncotarget, 2017 - ncbi.nlm.nih.gov
Oncolytic viruses (OVs) are viral strains that can infect and kill malignant cells while spare
their normal counterparts. OVs can access cells through binding to receptors on their surface …

The current status and future prospects of oncolytic viruses in clinical trials against melanoma, glioma, pancreatic, and breast cancers

IR Eissa, I Bustos-Villalobos, T Ichinose, S Matsumura… - Cancers, 2018 - mdpi.com
Oncolytic viral therapy has been accepted as a standard immunotherapy since talimogene
laherparepvec (T-VEC, Imlygic®) was approved by the Food and Drug Administration (FDA) …

[HTML][HTML] The emerging role of oncolytic virus therapy against cancer

L Russell, KW Peng - Chinese clinical oncology, 2018 - ncbi.nlm.nih.gov
This review discusses current clinical advancements in oncolytic viral therapy, with a focus
on the viral platforms approved for clinical use and highlights the benefits each platform …

[HTML][HTML] Oncolytic virus therapy in cancer: A current review

JS Apolonio, VL de Souza Gonçalves… - World journal of …, 2021 - ncbi.nlm.nih.gov
In view of the advancement in the understanding about the most diverse types of cancer and
consequently a relentless search for a cure and increased survival rates of cancer patients …

Recent advances in oncolytic virus-based cancer therapy

LQ Fu, SB Wang, MH Cai, XJ Wang, JY Chen, XM Tong… - Virus research, 2019 - Elsevier
Administration of oncolytic viruses (OVs) is an emerging anticancer strategy that exploits the
lytic nature of viral replication to enhance the killing of malignant cells. OVs can be used as …

Oncolytic viruses in cancer treatment: a review

SE Lawler, MC Speranza, CF Cho, EA Chiocca - JAMA oncology, 2017 - jamanetwork.com
Importance Oncolytic viruses (OVs) are emerging as important agents in cancer treatment.
Oncolytic viruses offer the attractive therapeutic combination of tumor-specific cell lysis …

Oncolytic virotherapy: Challenges and solutions

NH Goradel, AT Baker, A Arashkia, N Ebrahimi… - Current problems in …, 2021 - Elsevier
Viruses as cancer therapies have attracted attention since the 19th century. Scientists
observation that viruses can preferentially lyse cancer cells rather than healthy cells, created …