Abstract Background and Objective: Hyperleptinemia is supposed to play a causal role in
the development of obesity-associated hypertension, possibly via increased sympathetic …

Several studies have shown the association between obesity and hypertension. The
pathophysiologic mechanisms of obesity-related hypertension remain unknown. Clinical …

I have read with great interest the article by Tümer et al.[1] on the role of leptin in obesity-
associated hypertension. Previous studies have demonstrated that chronic leptin …

Leptin Does Not Mediate Hypertension Associated With Human Obesity: Cell Skip to Main
Content Advertisement Cell This journal offers authors two options (open access or subscription) …

Obesity in humans causes hypertension, myocardial hypertrophy and coronary
atherosclerosis, and increased cardiovascular morbidity and mortality that is thought to be …

Background: Obesity along with hypertension is the common risk factor for the development
of cardiovascular disease. Leptin, an anti-obesity hormone, is currently considered to play a …

Obesity is associated with increased cardiovascular morbidity and mortality, in part through
development of hypertension. Recent observations suggest that the cardiovascular actions …

Leptin is a protein produced by adipose tissue that acts in the central nervous system (CNS)
to decrease appetite and increase energy expenditure. Leptin thus functions as the afferent …

The potential actions of leptin in the pathophysiology of cardiovascular complications of
obesity are diverse, despite evidence of leptin resistance to its metabolic actions. However …

Obesity is associated with increased cardiovascular morbidity and mortality, in part through
development of hypertension. Recent observations suggest that the cardiovascular actions …