Outer surface protein polymorphisms linked to host‐spirochete association in Lyme borreliae
Lyme borreliosis is caused by multiple species of the spirochete bacteria Borrelia
burgdorferi sensu lato. The spirochetes are transmitted by ticks to vertebrate hosts, including …
burgdorferi sensu lato. The spirochetes are transmitted by ticks to vertebrate hosts, including …
Enzootic origins for clinical manifestations of Lyme borreliosis
Both early localized and late disseminated forms of Lyme borreliosis are caused by Borrelia
burgdorferi senso lato. Differentiating between the spirochetes that only cause localized skin …
burgdorferi senso lato. Differentiating between the spirochetes that only cause localized skin …
The role of Borrelia burgdorferi outer surface proteins
MR Kenedy, TR Lenhart… - FEMS Immunology & …, 2012 - academic.oup.com
Human pathogenic spirochetes causing Lyme disease belong to the Borrelia burgdorferi
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …
Antigenic variation in Borrelia: relapsing fever and Lyme borreliosis
AG Barbour - Antigenic variation, 2003 - Elsevier
Publisher Summary Relapsing fever (RF) was the first recognized example of antigenic
variation. The typical pattern of illness that was followed by recovery and relapse attracted …
variation. The typical pattern of illness that was followed by recovery and relapse attracted …
Insights into the biology of Borrelia burgdorferi gained through the application of molecular genetics
AM Groshong, JS Blevins - Advances in applied microbiology, 2014 - Elsevier
Borrelia burgdorferi, the vector-borne bacterium that causes Lyme disease, was first
identified in 1982. It is known that much of the pathology associated with Lyme borreliosis is …
identified in 1982. It is known that much of the pathology associated with Lyme borreliosis is …
Molecular and immunological analysis of a polymorphic periplasmic protein of Borrelia burgdorferi
WJ Simpson, ME Schrumpf, SF Hayes… - Journal of clinical …, 1991 - Am Soc Microbiol
Borrelia burgdorferi is the causative agent of Lyme disease, a tick-borne spirochetosis with a
worldwide prevalence. To assist the categorization and typing of fresh isolates from global …
worldwide prevalence. To assist the categorization and typing of fresh isolates from global …
Lyme borreliosis: host responses to Borrelia burgdorferi
A Szczepanski, JL Benach - Microbiological reviews, 1991 - Am Soc Microbiol
The chronic inflammatory condition that develops after infection by B. burgdorferi is a
complex process resulting from host responses to a limited number of organisms …
complex process resulting from host responses to a limited number of organisms …
Borrelia pathogenesis research in the post-genomic and post-vaccine era
A Nordstrand, AG Barbour, S Bergström - Current opinion in microbiology, 2000 - Elsevier
In the two years after publication of the genome sequence of Borrelia burgdorferi and reports
on human field trials of a vaccine against Lyme borreliosis, there has been further progress …
on human field trials of a vaccine against Lyme borreliosis, there has been further progress …
Recombination between genes encoding major outer surface proteins A and B of Borrelia burgdorferi
PA Rosa, T Schwan, D Hogan - Molecular microbiology, 1992 - Wiley Online Library
Borrelia burgdorferi causes Lyme disease, a multisystem illness that can persist in humans
for many years. We describe recombination between homologous genes encoding the …
for many years. We describe recombination between homologous genes encoding the …
Cryptic and Exposed Invariable Regions of VlsE, the Variable Surface Antigen of Borrelia burgdorferisl
FT Liang, JM Nowling, MT Philipp - Journal of bacteriology, 2000 - Am Soc Microbiol
Borrelia burgdorferi, the Lyme disease spirochete, possesses a surface protein, VlsE, which
undergoes antigenic variation. VlsE contains two invariable domains and a variable one that …
undergoes antigenic variation. VlsE contains two invariable domains and a variable one that …