[HTML][HTML] The role of epigenetics in placental development and the etiology of preeclampsia

C Apicella, CSM Ruano, C Méhats, F Miralles… - International journal of …, 2019 - mdpi.com
In this review, we comprehensively present the function of epigenetic regulations in normal
placental development as well as in a prominent disease of placental origin, preeclampsia …

Epigenetic processes during preeclampsia and effects on fetal development and chronic health

UM Ashraf, DL Hall, AZ Rawls, BT Alexander - Clinical Science, 2021 - portlandpress.com
Preeclampsia (PE), the leading cause of maternal and fetal morbidity and mortality, is
associated with poor fetal growth, intrauterine growth restriction (IUGR) and low birth weight …

The role of epigenetic changes in preeclampsia

A Kamrani, I Alipourfard, H Ahmadi‐Khiavi… - Biofactors, 2019 - Wiley Online Library
Preeclampsia (PE) is a disorder affecting 2–10% of pregnancies and has a major role for
perinatal and maternal mortality and morbidity. PE can be occurred by initiation of new …

Epigenetics and microRNAs in preeclampsia

M Choudhury, JE Friedman - Clinical and experimental …, 2012 - Taylor & Francis
Strong evidence suggests a potential link among epigenetics, microRNAs (miRNAs), and
pregnancy complications. Much research still needs to be carried out to determine whether …

[HTML][HTML] Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia

K Leavey, SL Wilson, SA Bainbridge, WP Robinson… - Clinical …, 2018 - Springer
Background Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy,
with no robust biomarkers or effective treatments. We hypothesized that this heterogeneity is …

[HTML][HTML] Landscape of transcriptional deregulations in the preeclamptic placenta

D Vaiman, R Calicchio, F Miralles - PloS one, 2013 - journals.plos.org
Preeclampsia is a pregnancy disease affecting 5 to 8% of pregnant women and a leading
cause of both maternal and fetal mortality and morbidity. Because of a default in the process …

[HTML][HTML] Epigenetics and preeclampsia: defining functional epimutations in the preeclamptic placenta related to the TGF-β pathway

E Martin, PD Ray, L Smeester, MR Grace, K Boggess… - PLoS …, 2015 - journals.plos.org
Preeclampsia is a potentially fatal pregnancy disorder affecting millions of women around
the globe. Dysregulation in gene and protein expression within key biological pathways …

[HTML][HTML] Early onset pre-eclampsia is associated with altered DNA methylation of cortisol-signalling and steroidogenic genes in the placenta

K Hogg, JD Blair, DE McFadden, P von Dadelszen… - PloS one, 2013 - journals.plos.org
Placental cortisol is inactivated in normotensive pregnancies, but is frequently present in pre-
eclampsia associated placentae. Since glucocorticoids are strongly associated with the …

[HTML][HTML] Differential methylation of genes associated with cell adhesion in preeclamptic placentas

L Anton, AG Brown, MS Bartolomei, MA Elovitz - PLoS One, 2014 - journals.plos.org
Preeclampsia (PE), a hypertensive disorder of pregnancy, is hypothesized to be associated
with, if not mechanistically related to abnormal placental function. However, the exact …

Genetic and epigenetic factors contribute to the onset of preeclampsia

ST Chelbi, D Vaiman - Molecular and cellular endocrinology, 2008 - Elsevier
Preeclampsia (PE) is a major cause of perinatal materno-foetal morbidity and pregnancy-
associated-mortality in industrialized countries. Clinically, PE associates maternal …