Immunotherapy in clinical canine leishmaniosis: a comparative update

M Baxarias, P Martínez-Orellana, G Baneth… - Research in veterinary …, 2019 - Elsevier
Leishmaniosis due to Leishmania infantum is a complex infection that can affect both
humans and dogs, and present a wide range of clinical signs and clinicopathological …

An overview of immunotherapeutic approaches against canine visceral leishmaniasis: what has been tested on dogs and a new perspective on improving treatment …

AAM Gonçalves, JC Leite, LA Resende… - Frontiers in Cellular …, 2019 - frontiersin.org
Visceral leishmaniasis (VL), caused by digenetic protozoa of the genus Leishmania, is the
most severe form of leishmaniasis. Leishmania infantum is one of the species responsible …

A blinded, randomized and controlled multicenter clinical trial to assess the efficacy and safety of Leisguard® as an immunotherapeutic treatment for healthy …

M Baxarias, G Donato, C Mateu, M Salichs… - Parasites & vectors, 2023 - Springer
Abstract Background Domperidone (Leisguard®) is an immunomodulatory drug used as a
preventive measure in healthy dogs. However, no studies have been published in healthy …

Insights on adaptive and innate immunity in canine leishmaniosis

S Hosein, DP Blake, L Solano-Gallego - Parasitology, 2017 - cambridge.org
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a
systemic disease, which can present with variable clinical signs, and clinicopathological …

Early reduction of Leishmania infantum-specific antibodies and blood parasitemia during treatment in dogs with moderate or severe disease

L Solano-Gallego, L Di Filippo, L Ordeix, M Planellas… - Parasites & …, 2016 - Springer
Background Leishmania infantum-specific antibodies are used extensively for the diagnosis
and monitoring of treatment in canine leishmaniosis. Different views have been described …

Effective immuno-therapeutic treatment of Canine Leishmaniasis

RAN Ramos, A Giannelli, F Fasquelle… - PLoS Neglected …, 2023 - journals.plos.org
Background Canine Leishmaniasis (CanL) caused by the L. infantum species is one of the
biggest threats to the health of the South American canine population. Chemotherapeutics …

Evaluation of a specific immunochemotherapy for the treatment of canine visceral leishmaniasis

JL Guarga, J Moreno, J Lucientes, MJ Gracia… - Veterinary Immunology …, 2002 - Elsevier
The efficacy of specific immunochemotherapy against Leishmania infantum infection in dog
was studied. The effects on transmission of the disease, as well as the cellular and humoral …

Canine leishmaniasis: an overview of the current status and strategies for control

RR Ribeiro, MSM Michalick, ME da Silva… - BioMed research …, 2018 - Wiley Online Library
Canine leishmaniasis (CanL) is a vector‐borne disease caused by Leishmania infantum
and is transmitted by female phlebotomine sand flies primarily between animals and …

An update on the diagnosis and treatment of canine leishmaniosis caused by Leishmania infantum (syn. L. chagasi)

C Noli, MN Saridomichelakis - The Veterinary Journal, 2014 - Elsevier
Canine leishmaniosis caused by Leishmania infantum is still a common disease in endemic
areas, such as the Mediterranean countries, and has progressively expanded into non …

An immune-modulating diet increases the regulatory T cells and reduces T helper 1 inflammatory response in Leishmaniosis affected dogs treated with standard …

L Cortese, M Annunziatella, AT Palatucci… - BMC veterinary …, 2015 - Springer
Background Clinical appearance and evolution of Canine Leishmaniosis (CL) are the
consequence of complex interactions between the parasite and the genetic and …