The emergence of disseminated metastases remains the primary cause of mortality in
cancer patients. Formation of the pre-metastatic niche (PMN), which precedes the …

Myeloid‐derived suppressor cells (MDSCs) are traditionally considered among the major
components of the immunosuppressive tumor microenvironment (TME). However, there is …

The tumor premetastatic niche initiated by primary tumors is constructed by multiple
molecular factors and cellular components and provides permissive condition that allows …

Myeloid-derived suppressor cells (MDSCs) represent a heterogenous population of
immature myeloid cells capable of modulating immune responses. In the context of cancer …

Tumor metastases represent the major cause of cancer-related mortality, confirming the
urgent need to identify key molecular pathways and cell-associated networks during the …

Accumulation of pathologically activated immature myeloid cells with potent immune-
suppressive activity is one of the major immunological hallmarks of cancer. In recent years, it …

Myeloid-derived suppressor cells (MDSCs) are one of the major negative regulators in tumor
microenvironment (TME) due to their potent immunosuppressive capacity. MDSCs are the …

Myeloid-derived suppressor cells (MDSC) represent a heterogeneous population of
immature myeloid cells. Under normal conditions, they differentiate into macrophages …

Myeloid derived suppressor cells (MDSCs) are a group of immature myeloid cells
accumulated in most cancer patients and mouse tumor models. MDSCs suppress host …

The mechanisms of distant metastasis of malignancies largely remain unknown. Circulating
tumor cells (CTC) derived from the primary cancer initiate distant metastasis by entering and …