A focused library of novel mannosylated glycophospholipids was synthesized employing
imidate coupling and H-phosphate phosphorylation methods. All novel glycophospholipids …

Phosphatidylinositol mannosides (PIMs) isolated from mycobacteria have been identified as
an important class of glycolipids with significant immune modulating properties. We present …

Phosphatidylinositol mannosides (PIMs) isolated from mycobacteria have been identified as
an important class of glycolipids with significant immune modulating properties. We present …

Glycolipid mimetics consisting of a bicyclic polyhydroxypiperidine-cyclic carbamate core and
a pseudoanomeric hydrophobic tail, termed sp 2-iminosugar glycolipids (sp 2-IGLs), target …

Phosphatidylinositol mannosides (PIMs) isolated from mycobacteria have been identified as
an important class of phosphoglycolipids with significant immune-modulating properties. We …

Abstract Development of simple and fully characterized immunomodulatory molecules is an
active area of research to enhance current immunotherapies. Monophosphoryl lipid A …

Adjuvant is an integral part of all vaccine formulations but only a few adjuvants with limited
efficacies or application scopes are available. Thus, developing more robust and diverse …

Glycolipids containing α-linked galactosyl and glucosyl moieties have been shown to
possess unique immunostimulatory activity creating a need for access to diverse and …

Glycolipids from Mycobacterium tuberculosis have a profound impact on the innate immune
response of the host. Macrophage‐inducible C‐type lectin (Mincle) is a pattern‐recognition …

Immunomodulatory glycolipids, among which α-galactosylceramide (KRN7000) is an iconic
example, have shown strong therapeutic potential in a variety of conditions ranging from …