Blood endotyping distinguishes the profile of vitiligo from that of other inflammatory and autoimmune skin diseases

T Czarnowicki, H He, A Leonard, HJ Kim… - Journal of Allergy and …, 2019 - Elsevier
Background Peripheral blood skin-homing/cutaneous lymphocyte antigen (CLA)+ T cells
emerge as biomarkers of cutaneous immune activation in patients with inflammatory skin …

Vitiligo skin biomarkers associated with favorable therapeutic response

Q Yang, G Zhang, M Su, G Leung, H Lui… - Frontiers in …, 2021 - frontiersin.org
Vitiligo is an acquired depigmentation skin disease caused by immune-mediated death of
melanocytes. The most common treatment for vitiligo is narrow band ultraviolet B …

Biomarkers of disease activity in vitiligo: A systematic review

R Speeckaert, M Speeckaert, S De Schepper… - Autoimmunity …, 2017 - Elsevier
The pathophysiology of vitiligo is complex although recent research has discovered several
markers which are linked to vitiligo and associated with disease activity. Besides providing …

Cytokines: the yin and yang of vitiligo pathogenesis

M Singh, A Kotnis, SD Jadeja, A Mondal… - Expert review of …, 2019 - Taylor & Francis
Introduction: Dysregulation of melanocyte function is associated with vitiligo, an idiopathic
autoimmune hypopigmentary skin disorder, caused by the selective destruction of …

[HTML][HTML] Immunophenotypic analysis reveals differences in circulating immune cells in the peripheral blood of patients with segmental and nonsegmental vitiligo

M Willemsen, NF Post, NOP van Uden… - Journal of Investigative …, 2022 - Elsevier
Accumulating studies have indicated immune-based destruction of melanocytes in both
segmental vitiligo (SV) and non-SV (NSV). Whereas SV often occurs unilaterally during …

immunology of vitiligo

J Seneschal, JE Harris, IC Le Poole… - Frontiers in …, 2021 - frontiersin.org
Several theories have been proposed to explain disease pathogenesis, considering the
roles of increased inflammatory and cytotoxic immune responses, neuropeptides …

Current concepts of vitiligo immunopathogenesis

N Hlača, T Žagar, M Kaštelan, I Brajac, L Prpić-Massari - Biomedicines, 2022 - mdpi.com
Vitiligo is an acquired immune-mediated disorder of pigmentation clinically characterized by
well-defined depigmented or chalk-white macules and patches on the skin. The prevalence …

Predominant role of innate pro-inflammatory cytokines in vitiligo disease

N Gholijani, MR Yazdani, L Dastgheib - Archives of dermatological …, 2020 - Springer
Vitiligo is a skin disorder with melanocyte destruction and an autoimmune basis. Given the
importance of cytokines in autoimmunity, we aimed to find the cytokine profile of innate and …

New insights into immune mechanisms of vitiligo.

K Boniface, A Taieb, J Seneschal - Giornale Italiano di Dermatologia …, 2015 - europepmc.org
Vitiligo is the most common depigmenting disorder, affecting 0.5% of the population. This
stigmatizing disease has a major social impact with high unmet needs, and no real curative …

Cytokine profile (IL‐2, IL‐6, IL‐17, IL‐22, and TNF‐α) in vitiligo—New insight into pathogenesis of disease

S Sushama, N Dixit, RK Gautam, P Arora… - Journal of Cosmetic …, 2019 - Wiley Online Library
Background Vitiligo is an autoimmune disease associated with alteration in levels of various
cytokines. However, there are very few studies in this regard. Objectives To assess the …