Osteoarticular infections include septic arthritis and osteomyelitis, with Gram-positive
microorganisms isolated most frequently. In recent years, there has been an increase in the …

Introduction Fosfomycin is a wide spectrum bactericidal antibiotic with a unique mode of
action, low toxicity, and good penetration in tissues with deep-seated infections, including …

The therapeutic effectiveness of adjuvant therapy with fosfomycin was studied in a
prospective clinical trial of 60 patients suffering from chronic posttraumatic osteomyelitis. The …

The treatment of bacterial infections suffers from two major problems: spread of multidrug-
resistant (MDR) or extensively drug-resistant (XDR) pathogens and lack of development of …

In recent years, heavy drug resistance in bacteria has become increasingly serious, and the
progress of research and development of new antibiotics are slow. Therefore, seeking an …

Fosfomycin, an antibiotic discovered in Spain, has a unique chemical structure and
pharmacologic features that are promising for clinical therapy. It is only partially absorbed …

Fosfomycin was exclusively used as antibiotic treatment in 37 patients suffering from
osteomyelitis, out of which 23 were operated for sequestrectomy or fistulectomy, whereas …

Due to the increase in antimicrobial resistance, strategies such as antimicrobial stewardship
programs (ASP) have been developed to improve the clinical results, decrease the adverse …

Fosfomycin is a bactericidal antibiotic that interferes with cell wall synthesis. The drug
therefore has a broad spectrum of activity against a wide range of Gram-positive and Gram …

Fosfomycin is gaining interest in the treatment of complex osteoarticular infections (OI) due
to multidrug-resistant (MDR) pathogens. Our aims were to conduct population …