Herpes simplex virus type 1 (HSV-1) infection activates a rapid stimulation of host innate
immune responses and a delicate interplay between virus and host immune elements …

SUMMARY Herpes simplex virus 1 (HSV-1) is very successful in establishing acute and
latent infections in humans by counteracting host antiviral innate immune responses. HSV-1 …

Herpes simplex virus (HSV), a human pathogenic virus, has evolved several strategies to
evade the production and function of interferons (IFNs) and cytokines generated by the …

Innate immune responses play a major role in the control of herpes simplex virus (HSV)
infections, and a multiplicity of mechanisms have emerged as a result of human evolution to …

The interferon (IFN) system is one of the first lines of defense activated against invading viral
pathogens. Upon secretion, IFNs activate a signaling cascade resulting in the production of …

Herpes simplex virus type 1 (HSV-1) infection triggers a rapid induction of host innate
immune responses. The type I interferon (IFN) signal pathway is a central aspect of host …

Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) have co-evolved with humans for
thousands of years and are present at a high prevalence in the population worldwide. HSV …

Immune responses against HSV-1 and HSV-2 are complex and involve a delicate interplay
between innate signaling pathways and adaptive immune responses. The innate response …

Infection with herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) is extremely
frequent in the human population, as well as recurrent reactivations due to lifelong infection …

The interaction between herpes simplex virus type 1 (HSV-1) and its host starts with the
attachment of the virus for entry and spreading into host cells involving viral glycoproteins …