Haematopoietic stem cells (HSCs) are maintained by bone marrow niches in vivo,, but the
ability of niche cells to maintain HSCs ex vivo is markedly diminished. Expression of niche …

Multiple bone marrow stromal cell types have been identified as hematopoietic stem cell
(HSC)-regulating niche cells,,,,,,. However, whether HSC progeny can serve directly as HSC …

Hematopoietic stem cell (HSC) transplantation represents a curative treatment for various
hematological disorders. However, delayed reconstitution of innate and adaptive immunity …

Hematopoietic stem cells (HSCs) reside in and are maintained by special
microenvironments, termed niches. It is assumed that the HSC niche space remains …

Arterioles and sinusoids of the bone marrow (BM) are accompanied by stromal cells that
express nerve/glial antigen 2 (NG2) and leptin receptor (LepR), and constitute specialized …

Hematopoiesis provides a suitable model for understanding adult stem cells and their niche.
Hematopoietic stem cells (HSCs) continuously produce blood cells through orchestrated …

Stem cell niches are specialized microenvironments that promote the maintenance of stem
cells and regulate their function. Recent advances have improved our understanding of the …

In the bone marrow, hematopoietic stem cells (HSCs) are maintained by special
microenvironments, termed niches. The nature and function of these niches, however …

Mesenchymal stem cells (MSCs) have been extensively used for cell therapies and tissue
engineering. The current MSC strategy requires a large quantity of cells for such …

Hematopoietic stem cell (HSC) transplantation can restore a new functional hematopoietic
system in recipients in cases where the system of the recipient is not functional or for …