Comparative risk of venous thromboembolism in rheumatoid arthritis patients receiving tofacitinib versus those receiving tumor necrosis factor inhibitors: an …
Objective To evaluate the risk of venous thromboembolism (VTE) in rheumatoid arthritis (RA)
patients receiving tofacitinib versus those receiving tumor necrosis factor (TNF) inhibitors …
patients receiving tofacitinib versus those receiving tumor necrosis factor (TNF) inhibitors …
Risk of venous thromboembolism associated with tofacitinib in patients with rheumatoid arthritis: a population-based cohort study
Objective To evaluate the risk of venous thromboembolism (VTE) with tofacitinib compared
with TNFis in patients with RA. Methods RA patients initiating tofacitinib or a TNFi without …
with TNFis in patients with RA. Methods RA patients initiating tofacitinib or a TNFi without …
Risk of Venous Thromboembolism With Tofacitinib Versus Tumor Necrosis Factor Inhibitors in Cardiovascular Risk‐Enriched Rheumatoid Arthritis Patients
C Charles‐Schoeman, R Fleischmann… - Arthritis & …, 2024 - Wiley Online Library
Objective. The ORAL Surveillance trial found a dose-dependent increase in venous
thromboembolism (VTE) and pulmonary embolism (PE) events with tofacitinib versus tumor …
thromboembolism (VTE) and pulmonary embolism (PE) events with tofacitinib versus tumor …
Biomarkers to predict risk of venous thromboembolism in patients with rheumatoid arthritis receiving tofacitinib or tumour necrosis factor inhibitors
JI Weitz, Z Szekanecz, C Charles-Schoeman… - RMD open, 2022 - rmdopen.bmj.com
Objective In the ORAL (Oral Rheumatoid Arthritis triaL) Surveillance study of patients with
rheumatoid arthritis aged≥ 50 years with≥ 1 additional cardiovascular risk factor, incidence …
rheumatoid arthritis aged≥ 50 years with≥ 1 additional cardiovascular risk factor, incidence …
Incidence of venous and arterial thromboembolic events reported in the tofacitinib rheumatoid arthritis, psoriasis and psoriatic arthritis development programmes and …
P Mease, C Charles-Schoeman, S Cohen… - Annals of the …, 2020 - ard.bmj.com
Objectives Tofacitinib is a Janus kinase inhibitor for the treatment of rheumatoid arthritis
(RA), psoriatic arthritis (PsA) and ulcerative colitis, and has been investigated in psoriasis …
(RA), psoriatic arthritis (PsA) and ulcerative colitis, and has been investigated in psoriasis …
Risk of major adverse cardiovascular events with tofacitinib versus tumour necrosis factor inhibitors in patients with rheumatoid arthritis with or without a history of …
C Charles-Schoeman, MH Buch… - Annals of the …, 2023 - ard.bmj.com
Objectives Evaluate risk of major adverse cardiovascular events (MACE) with tofacitinib
versus tumour necrosis factor inhibitors (TNFi) in patients with rheumatoid arthritis (RA) with …
versus tumour necrosis factor inhibitors (TNFi) in patients with rheumatoid arthritis (RA) with …
Rheumatoid arthritis disease activity and adverse events in patients receiving tofacitinib or tumor necrosis factor inhibitors: a post hoc analysis of ORAL Surveillance
GA Karpouzas, Z Szekanecz… - Therapeutic …, 2023 - journals.sagepub.com
Background: In patients with rheumatoid arthritis (RA), persistent inflammation and
increasing disease activity are associated with increased risk of adverse events (AEs) …
increasing disease activity are associated with increased risk of adverse events (AEs) …
Cardiovascular and cancer risk with tofacitinib in rheumatoid arthritis
SR Ytterberg, DL Bhatt, TR Mikuls… - … England Journal of …, 2022 - Mass Medical Soc
Background Increases in lipid levels and cancers with tofacitinib prompted a trial of major
adverse cardiovascular events (MACE) and cancers in patients with rheumatoid arthritis …
adverse cardiovascular events (MACE) and cancers in patients with rheumatoid arthritis …
Tofacitinib and risk of cardiovascular outcomes: results from the Safety of TofAcitinib in Routine care patients with Rheumatoid Arthritis (STAR-RA) study
F Khosrow-Khavar, SC Kim, H Lee, SB Lee… - Annals of the rheumatic …, 2022 - ard.bmj.com
Objectives Recent results from 'ORAL Surveillance'trial have raised concerns regarding the
cardiovascular safety of tofacitinib in patients with rheumatoid arthritis (RA). We further …
cardiovascular safety of tofacitinib in patients with rheumatoid arthritis (RA). We further …
Malignancy risk with tofacitinib versus TNF inhibitors in rheumatoid arthritis: results from the open-label, randomised controlled ORAL Surveillance trial
JR Curtis, K Yamaoka, YH Chen, DL Bhatt… - Annals of The …, 2023 - ard.bmj.com
Objectives To evaluate malignancies and their associations with baseline risk factors and
cardiovascular risk scores with tofacitinib versus tumour necrosis factor inhibitors (TNFi) in …
cardiovascular risk scores with tofacitinib versus tumour necrosis factor inhibitors (TNFi) in …
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