[PDF][PDF] CCL 15 Recruits Suppressive Monocytes to Facilitate Immune Escape and Disease Progression in Hepatocellular Carcinoma
Chemokines play a key role in orchestrating the recruitment and positioning of myeloid cells
within the tumor microenvironment. However, the tropism regulation and functions of these …
within the tumor microenvironment. However, the tropism regulation and functions of these …
Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma
Objective Hepatocellular carcinoma (HCC) is an aggressive malignancy with limited
effective treatment options. An alternative strategy is to target cells, such as tumour …
effective treatment options. An alternative strategy is to target cells, such as tumour …
[HTML][HTML] Biological and clinical significance of the CCR5/CCL5 axis in hepatocellular carcinoma
Despite the improvement in survival for patients with liver cancer (LCa) in recent decades,
only one in five patients survive for 5 years after diagnosis. Thus, there is an urgent need to …
only one in five patients survive for 5 years after diagnosis. Thus, there is an urgent need to …
CCL20, a direct-acting pro-angiogenic chemokine induced by hepatitis C virus (HCV): Potential role in HCV-related liver cancer
M Benkheil, M Van Haele, T Roskams… - Experimental Cell …, 2018 - Elsevier
Abstract The CCL20/CCR6 chemokine/receptor axis has previously been shown to
contribute to the initiation and progression of hepatocellular carcinoma (HCC) through the …
contribute to the initiation and progression of hepatocellular carcinoma (HCC) through the …
[PDF][PDF] Inflammation‐induced hepatocellular carcinoma is dependent on CCR5 in mice
N Barashi, ID Weiss, O Wald, H Wald, K Beider… - …, 2013 - Wiley Online Library
Human hepatocellular carcinoma (HCC) is an inflammation‐induced cancer, which is the
third‐leading cause of cancer mortality worldwide. We investigated the role of the …
third‐leading cause of cancer mortality worldwide. We investigated the role of the …
[HTML][HTML] CCL14 is a prognostic biomarker and correlates with immune infiltrates in hepatocellular carcinoma
Y Gu, X Li, Y Bi, Y Zheng, J Wang, X Li, Z Huang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
CC motif chemokine ligand 14 (CCL14) is a chemokine promoting the activation of immune
cells. However, the relationship between CCL14 expression, tumor immunity, and prognosis …
cells. However, the relationship between CCL14 expression, tumor immunity, and prognosis …
Chemokine receptor CCR7 enhances intrahepatic and lymphatic dissemination of human hepatocellular cancer
CC Schimanski, R Bahre, I Gockel… - Oncology …, 2006 - spandidos-publications.com
Despite many pathophysiological analyses, the process of tumor dissemination of
hepatocellular carcinoma (HCC) remains vague. In diverse tumor entities, expression of the …
hepatocellular carcinoma (HCC) remains vague. In diverse tumor entities, expression of the …
[HTML][HTML] CCL14 serves as a novel prognostic factor and tumor suppressor of HCC by modulating cell cycle and promoting apoptosis
M Zhu, W Xu, C Wei, J Huang, J Xu, Y Zhang… - Cell death & …, 2019 - nature.com
CCL14 is a member of CC chemokines and its role in hepatocellular carcinoma (HCC) is still
unknown. In this study, CCL14 expression were analyzed by tissue microarray (TMA) …
unknown. In this study, CCL14 expression were analyzed by tissue microarray (TMA) …
[HTML][HTML] The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation
Q Wu, J Chen, Y Chen, L Cai, X Wang, W Guo… - Cell Death & …, 2018 - nature.com
G-protein-coupled receptor (GPCR)-related proteins are dysregulated and the GPCR CC-
chemokine receptor 10 (CCR10) is significantly upregulated in inflammation-driven HCC …
chemokine receptor 10 (CCR10) is significantly upregulated in inflammation-driven HCC …
Blocking the CCL2–CCR2 axis using CCL2-neutralizing antibody is an effective therapy for hepatocellular cancer in a mouse model
Hepatocellular carcinoma, a deadly disease, commonly arises in the setting of chronic
inflammation. CC motif chemokine ligand 2 (CCL2/MCP1), a chemokine that recruits CCR2 …
inflammation. CC motif chemokine ligand 2 (CCL2/MCP1), a chemokine that recruits CCR2 …