The what, where and how of delay activity

KK Sreenivasan, M D'Esposito - Nature reviews neuroscience, 2019 - nature.com
Working memory is characterized by neural activity that persists during the retention interval
of delay tasks. Despite the ubiquity of this delay activity across tasks, species and …

Mechanisms of persistent activity in cortical circuits: possible neural substrates for working memory

J Zylberberg, BW Strowbridge - Annual review of neuroscience, 2017 - annualreviews.org
A commonly observed neural correlate of working memory is firing that persists after the
triggering stimulus disappears. Substantial effort has been devoted to understanding the …

Perturbing neural representations of working memory with task-irrelevant interruption

N Hakim, T Feldmann-Wüstefeld, E Awh… - Journal of Cognitive …, 2020 - direct.mit.edu
Working memory maintains information so that it can be used in complex cognitive tasks. A
key challenge for this system is to maintain relevant information in the face of task-irrelevant …

The importance of single-trial analyses in cognitive neuroscience

M Stokes, E Spaak - Trends in Cognitive Sciences, 2016 - cell.com
Theories of working memory typically assume that information is maintained via persistent
neural activity. By contrast, Lundqvist et al. report that single-trial delay activity is actually …

Is activity silent working memory simply episodic memory?

AO Beukers, TJ Buschman, JD Cohen… - Trends in cognitive …, 2021 - cell.com
Working memory (WM) maintains task-relevant information in a state ready for processing.
While traditional theories assume that sustained neuronal activity is responsible for WM, the …

Working memory: delay activity, yes! Persistent activity? Maybe not

M Lundqvist, P Herman, EK Miller - Journal of neuroscience, 2018 - Soc Neuroscience
Persistent spiking has been thought to underlie working memory (WM). However, virtually all
of the evidence for this comes from studies that averaged spiking across time and across …

Persistent spiking activity underlies working memory

C Constantinidis, S Funahashi, D Lee… - Journal of …, 2018 - Soc Neuroscience
Persistent activity generated in the PFC during the delay period of working memory tasks
represents information about stimuli held in memory and determines working memory …

The influence of memory load upon delay-interval activity in a working-memory task: an event-related functional MRI study

AP Jha, G McCarthy - Journal of Cognitive Neuroscience, 2000 - direct.mit.edu
We conducted two fMRI studies to investigate the sensitivity of delay-period activity to
changes in memory load during a delayed-recognition task for faces. In Experiment 1, each …

Working memory as an emergent property of the mind and brain

BR Postle - Neuroscience, 2006 - Elsevier
Cognitive neuroscience research on working memory has been largely motivated by a
standard model that arose from the melding of psychological theory with neuroscience data …

[HTML][HTML] The role of prefrontal cortex in working memory: a mini review

AH Lara, JD Wallis - Frontiers in systems neuroscience, 2015 - frontiersin.org
A prominent account of prefrontal cortex (PFC) function is that single neurons within the PFC
maintain representations of task-relevant stimuli in working memory. Evidence for this view …