[HTML][HTML] Combination of L-Arginine and L-Norvaline protects against pulmonary fibrosis progression induced by bleomycin in mice

L Gao, JH Zhang, XX Chen, HL Ren, XL Feng… - Biomedicine & …, 2019 - Elsevier
Pulmonary fibrosis (PF) progression may be involved with arginine (Arg) metabolism and
immune balance. The present study aimed to explore the effects of L-Arginine (L-Arg) and L …

L-arginine mitigates bleomycin-induced pulmonary fibrosis in rats through regulation of HO-1/PPAR-γ/β-catenin axis

NA Alhakamy, AJ Alamoudi, HZ Asfour… - International …, 2024 - Elsevier
Pulmonary fibrosis is a chronic and progressively deteriorating lung condition that can be
replicated in laboratory animals by administering bleomycin, a chemotherapeutic antibiotic …

[HTML][HTML] Sinapic acid ameliorates bleomycin-induced lung fibrosis in rats

M Raish, A Ahmad, MA Ansari, A Ahad… - Biomedicine & …, 2018 - Elsevier
Background Pulmonary fibrosis is a multifaceted disease with high mortality and morbidity,
and it is commonly nonresponsive to conventional therapy. Purpose We explore the …

N-acetylcysteine downregulation of lysyl oxidase activity alleviating bleomycin-induced pulmonary fibrosis in rats

S Li, X Yang, W Li, J Li, X Su, L Chen, G Yan - Respiration, 2012 - karger.com
Background: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease
without beneficial therapy, except for lung transplantation. A high oral dose of N …

Ameliorating effect of erythromycin on bleomycin‐induced pulmonary fibrosis: Role of alveolar macrophage activation and cytokine release

B CHEN, L Jiang, W Zhao, R Yu, XM Hou - Respirology, 1997 - Wiley Online Library
The objective of this study was to evaluate the effectiveness of erythromycin (EM) on
bleomycin‐induced pulmonary fibrosis in rats and its possible mechanisms. Seventy‐five …

Possible modulatory role of nitric oxide in lung toxicity induced in rats by chronic administration of bleomycin

AS El-Khatib - Chemotherapy, 2002 - karger.com
Background: The present study was undertaken to evaluate whether stimulation or inhibition
of nitric oxide (NO) synthesis could affect lung toxicity induced by chronic administration of …

[HTML][HTML] The effects of chronic intermittent hypoxia in bleomycin-induced lung injury on pulmonary fibrosis via regulating the NF-κB/Nrf2 signaling pathway

HH Kang, IK Kim, CD Yeo, SW Kim… - Tuberculosis and …, 2020 - ncbi.nlm.nih.gov
Background Obstructive sleep apnea (OSA) is associated with pulmonary fibrosis. Chronic
intermittent hypoxia (CIH) is considered to be a surrogate of OSA. However, its exact role in …

[HTML][HTML] Andrographolide plays an important role in bleomycin-induced pulmonary fibrosis treatment

JN Yin, YN Li, Y Gao, SB Li, JD Li - International Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Pulmonary fibrosis (PF) leads to chronic inflammation and accumulation of macrophages,
neutrophils, and lymphocytes in the alveoli. The factors involved in the development of PF …

RETRACTED ARTICLE: Qilongtian ameliorate bleomycin-induced pulmonary fibrosis in mice via inhibiting IL-17 signal pathway

Q Zhang, T Luo, D Yuan, J Liu, Y Fu, J Yuan - Scientific reports, 2023 - nature.com
Pulmonary fibrosis (PF) is a special type of pulmonary parenchymal disease, with chronic,
progressive, fibrosis, and high mortality. There is a lack of safe, effective, and affordable …

Combination of losartan with pirfenidone: a protective anti-fibrotic against pulmonary fibrosis induced by bleomycin in rats

A Amirkhosravi, M Mirtajaddini Goki, MR Heidari… - Scientific Reports, 2024 - nature.com
Pirfenidone (PFD), one acceptable medication for treating idiopathic pulmonary fibrosis
(IPF), is not well tolerated by patients at full doses. Hence, employing of some approaches …