Curcumin and heme oxygenase: neuroprotection and beyond

E Mhillaj, A Tarozzi, L Pruccoli, V Cuomo… - International journal of …, 2019 - mdpi.com
Curcumin is a natural polyphenol component of Curcuma longa Linn, which is currently
considered one of the most effective nutritional antioxidants for counteracting free radical …

Curcumin, hormesis and the nervous system

M Concetta Scuto, C Mancuso, B Tomasello… - Nutrients, 2019 - mdpi.com
Curcumin is a polyphenol compound extracted from the rhizome of Curcuma longa Linn
(family Zingiberaceae) commonly used as a spice to color and flavor food. Several …

Ameliorating potential of curcumin and its analogue in central nervous system disorders and related conditions: a review of molecular pathways

P Joshi, A Bisht, S Joshi, D Semwal… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin, isolated from turmeric (Curcuma longa L.) is one of the broadly studied
phytomolecule owing to its strong antioxidant and anti‐inflammatory potential and has been …

A state of the art of antioxidant properties of curcuminoids in neurodegenerative diseases

S Silvestro, C Sindona, P Bramanti… - International Journal of …, 2021 - mdpi.com
Neurodegenerative diseases represent a set of pathologies characterized by an irreversible
and progressive, and a loss of neuronal cells in specific areas of the brain. Oxidative …

Curcumin activates defensive genes and protects neurons against oxidative stress

G Scapagnini, C Colombrita, M Amadio… - Antioxidants & redox …, 2006 - liebertpub.com
Spices and herbs often contain active phenolic substances endowed with potent
antioxidative properties. We had previously shown that curcumin, the yellow pigment in …

Curcumin pretreatment induces Nrf2 and an antioxidant response and prevents hemin‐induced toxicity in primary cultures of cerebellar granule neurons of rats

S González-Reyes, S Guzmán-Beltrán… - Oxidative medicine …, 2013 - Wiley Online Library
Curcumin is a bifunctional antioxidant derived from Curcuma longa. This study identifies
curcumin as a neuroprotectant against hemin‐induced damage in primary cultures of …

Antioxidant effects of curcumin in models of neurodegeneration, aging, oxidative and nitrosative stress: A review

S Abrahams, WL Haylett, G Johnson, JA Carr… - Neuroscience, 2019 - Elsevier
The global burden of neurodegenerative disorders has increased substantially over the past
2 decades due to rising rates of population aging. Although neurodegenerative disorders …

Antioxidant, anti‐inflammatory and epigenetic potential of curcumin in Alzheimer's disease

T Abdul‐Rahman, WA Awuah, T Mikhailova… - …, 2024 - Wiley Online Library
Alzheimer's disease (AD) constitutes a multifactorial neurodegenerative pathology
characterized by cognitive deterioration, personality alterations, and behavioral shifts. The …

New promising therapeutic avenues of curcumin in brain diseases

T Benameur, G Giacomucci, MA Panaro, M Ruggiero… - Molecules, 2021 - mdpi.com
Curcumin, the dietary polyphenol isolated from Curcuma longa (turmeric), is commonly used
as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also …

Curcumin, gut microbiota, and neuroprotection

F Di Meo, S Margarucci, U Galderisi, S Crispi, G Peluso - Nutrients, 2019 - mdpi.com
Curcumin, a nontoxic, naturally occurring polyphenol, has been recently proposed for the
management of neurodegenerative and neurological diseases. However, a discrepancy …