[PDF][PDF] Investigation of novel biomarkers and treatment strategies in steroid-resistant nephrotic syndrome

E Sen - 2019 - research-information.bris.ac.uk
Steroid-resistant nephrotic syndrome (SRNS) is a heterogeneous condition with significant
numbers of patients progressing to end-stage renal failure (ESRF) requiring transplantation …

Genetic testing in steroid-resistant nephrotic syndrome: when and how?

S Lovric, S Ashraf, W Tan… - Nephrology Dialysis …, 2016 - academic.oup.com
Steroid-resistant nephrotic syndrome (SRNS) represents the second most frequent cause of
chronic kidney disease in the first three decades of life. It manifests histologically as focal …

Use of genomic and functional analysis to characterize patients with steroid-resistant nephrotic syndrome

TM Kitzler, N Kachurina, MM Bitzan, E Torban… - Pediatric …, 2018 - Springer
Background Children with genetic causes of steroid-resistant nephrotic syndrome (SRNS)
usually do well after renal transplantation, while some with idiopathic SRNS show …

Look alike, sound alike: phenocopies in steroid-resistant nephrotic syndrome

F Becherucci, S Landini, L Cirillo, B Mazzinghi… - International journal of …, 2020 - mdpi.com
Steroid-resistant nephrotic syndrome (SRNS) is a clinical picture defined by the lack of
response to standard steroid treatment, frequently progressing toward end-stage kidney …

Biomarkers to predict steroid resistance in idiopathic nephrotic syndrome: a systematic review

CJ May, NP Ford - bioRxiv, 2023 - biorxiv.org
In this systematic review we have sought to summarise the current knowledge concerning
biomarkers that can distinguish between steroid-resistant nephrotic syndrome and steroid …

Exploring the clinical and genetic spectrum of steroid resistant nephrotic syndrome: the PodoNet registry

A Trautmann, BS Lipska-Ziętkiewicz… - Frontiers in …, 2018 - frontiersin.org
Background: Steroid resistant nephrotic syndrome (SRNS) is a rare condition, accounting for
10–15% of all children with idiopathic nephrotic syndrome. SRNS can be caused by genetic …

Steroid-resistant nephrotic syndrome in children: A mini-review on genetic mechanisms, predictive biomarkers and pharmacotherapy strategies

HL Guo, L Li, ZY Xu, X Jing, Y Xia… - Current …, 2021 - ingentaconnect.com
Steroid-resistant nephrotic syndrome (SRNS) constitutes the second most frequent cause of
chronic kidney disease in childhood. The etiology of SRNS remains largely unknown and no …

Genetic testing in steroid-resistant nephrotic syndrome: why, who, when and how?

R Preston, HM Stuart, R Lennon - Pediatric nephrology, 2019 - Springer
Steroid-resistant nephrotic syndrome (SRNS) is a common cause of chronic kidney disease
in childhood and has a significant risk of rapid progression to end-stage renal disease. The …

The importance of genetic study in steroid-resistant nephrotic syndrome

SZ Vahed, HM Sani, S Rajabzadeh… - Journal of Renal Injury …, 2019 - journalrip.com
Steroid-resistant nephrotic syndrome (SRNS) is a challenging clinical task. It has
heterogeneous etiology and extremely variable clinical outcomes and generally progresses …

Targeted gene panel for genetic testing of south Indian children with steroid resistant nephrotic syndrome

A Siji, KN Karthik, VC Pardeshi, PS Hari… - BMC Medical …, 2018 - Springer
Background Steroid resistant nephrotic syndrome (SRNS) is a genetically heterogeneous
disease with significant phenotypic variability. More than 53 podocyte-expressed genes are …