Objective: We investigated microsatellite instability (MSI) status and programed cell death
ligand 1 (PD-L1) expression as predictors of prognosis and responsiveness to …

Background Patients with high microsatellite instability (MSI) gastric cancer (GC) show
improved survival and no benefit or harm from adjuvant and/or perioperative chemotherapy …

This study investigated whether MSI status can be used as a prognostic biomarker and
whether it is helpful for predicting which patients will benefit from 5‐FU based adjuvant …

Gastric cancer is one of the most aggressive malignancies, with limited treatment options in
both locally advanced and metastatic setting, resulting in poor prognosis. Based on genomic …

Abstract Programmed death-ligand 1 (PD-L1) is expressed in a subgroup of gastric cancers
that may benefit from immunotherapy. Microsatellite instability-high (MSI-H) is a potential …

Background Microsatellite instability (MSI) and programmed death-ligand 1 (PD-L1) are
candidate predictors for the response to immune checkpoint inhibitors, and may predict …

We previously reported that the prognosis of microsatellite instability high (MSI‐H) gastric
cancer is similar to that of MSI‐low/microsatellite stable (MSI‐L/MSS) gastric cancer. The …

Introduction Conflicting data exist regarding the relevance of high-frequency microsatellite
instability (MSI-H) for predicting the prognosis and benefits of 5-fluorouracil (5-FU)-based …

PURPOSE In the CLASSIC and MAGIC trials, microsatellite instability (MSI)–high status was
a favorable prognostic and potential negative predictive factor for neoadjuvant/adjuvant …

Perioperative systemic treatment is standard of care for Caucasian patients with locally
advanced, resectable gastric adenocarcinoma. The prognostic relevance of the …