Abstract Background Intrarenal calcium oxalate (CaOx) crystals induce inflammation and
kidney tubular cell injury, which are processes that involve TLR4/NF-κB signalling. A recent …

Long noncoding RNA (lncRNA) has been suggested to play an important role in a variety of
diseases over the past decade. In a previous study, we identified a novel lncRNA, termed …

Intrarenal calcium oxalate (CaOx) crystals induce renal tubular epithelial cells (TECs) injury
and inflammation, which involve Toll-like receptor 4 (TLR4)/interferon regulatory factor 1 …

Aims: Calcium oxalate (CaOx) crystal deposition induces damage to the renal tubular
epithelium, increases epithelial adhesion, and contributes to CaOx nephrocalcinosis. The …

Randall plaques (RPs) can contribute to the formation of idiopathic calcium oxalate (CaOx)
kidney stones; however, genes related to RP formation have not been identified. We …

Background/Aims: The aim of this study was to elucidate how high-mobility group box 1
(HMGB1) exacerbates renal ischemic-reperfusion injury (IRI) by inflammatory and immune …

Kidney stone disease is a crystal concretion formed in the kidneys that has been associated
with an increased risk of chronic kidney disease. MicroRNAs are functionally involved in …

Calcium oxalate (CaOx) crystal can trigger kidney injury, which contributes to the
pathogenesis of nephrocalcinosis. The phenotypes of infiltrating macrophage may impact …

Background Calcium oxalate monohydrate (COM) is the major crystalline component in
kidney stones and its adhesion to renal tubular cells leads to tubular injury. However, COM …

With the rapid development of imaging diagnosis and interventional therapy, contrast media
(CM) are widely used in clinics. However, contrast-induced nephropathy (CIN) is the third …