Objectives: α-lipoic acid (ALA) is a natural antioxidant which acts as a cofactor of
bioenergetic mitochondrial enzymes. Along with its mitochondrial action, ALA and its …

Despite the existence of many preclinical studies, scientific evidence is lacking on the
clinical use of alpha-lipoic acid (ALA) for central nervous system disorders. Therefore, we …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that destroys patient
memory and cognition, communication ability with the social environment and the ability to …

The naturally occurring antioxidant lipoic acid (LA) was first described as an essential
cofactor for the conversion of pyruvate to Acetyl-CoA, a critical step in respiration. LA is now …

Alpha-lipoic acid is a naturally occurring substance, essential for the function of different
enzymes that take part in mitochondria's oxidative metabolism. It is believed that alpha-lipoic …

Background The molecular nature of lipoic acid (LA) clarifies its capability of taking part to a
variety of biochemical reactions where redox state is meaningful. The pivotal action of LA is …

Alpha-lipoic acid (ALA) is a potent antioxidant used in the management of diabetic
neuropathy due to its ability to prevent neuronal lipid peroxidation. ALA also chelates …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that destroys patient
memory and cognition, communication ability with the social environment and the ability to …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases with
motor disturbances, cognitive decline, and behavioral impairment. It is characterized by the …

Polyunsaturated fatty acids (PUFAs) are crucial for our health and wellbeing; therefore, they
have been widely investigated for their roles in maintaining human health and in disease …