Objectives: Describe the mechanism of action of the aminoglycosides. Outline the
indications for different aminoglycosides. Summarize the adverse effects and monitoring …

Since the introduction into clinical practice of the aminoglycoside class of antibiotics, a
number of other antimicrobial agents with improved safety profile have entered the market …

Resistant bacteria have renewed our interest in the aminoglycoside drugs. Evidence on the
efficiency of aminoglycosides in their different clinical uses is available from numerous …

The aminoglycosidic aminocyclitols have been utilized extensively for three decades.
Nonetheless, the future use of this class of agents has been questioned of late. Recognized …

Aminoglycosides: how should we use them in the 21st century? : Current Opinion in Infectious
Diseases Aminoglycosides: how should we use them in the 21st century? : Current Opinion in …

Aminoglycosides are natural or semisynthetic antibiotics derived from actinomycetes. They
were among the first antibiotics to be introduced for routine clinical use and several …

Aminoglycosides remain a mainstay of antimicrobial therapy, especially for treatment of
serious Gram-negative infections. Aminoglycosides represent cornerstone of antibiotic …

Recently, a more complete understanding of the pharmacodynamics of aminoglycosides
has been recognized, indicating that this class of antibiotics exhibits both concentration …

Abstract The new Australian Therapeutic Guidelines: Antibiotic, version 14 have revised the
recommendations for the use and monitoring of aminoglycosides. The guidelines have clear …

More than a decade has passed since the first observations that the dosing strategies for
aminoglycoside administration influenced the development of aminoglycoside toxicity [1] …