Dry powder inhalers (DPIs) are known to be sensitive to humidity. Erroneous storage of
these products by patients in high humidity environments, could present a potential risk …

The use of physiologically based pharmacokinetic (PBPK) models to support drug product
development has become increasingly popular. The in vitro characterization of the materials …

In vitro assessment of dry powders for inhalation (DPIs) aerodynamic performance is an
inevitable test in DPI development. However, contemporary trends in drug development also …

Multi-dose dry powder inhalers (DPIs) are commonly used in asthma and chronic obstructive
lung disease (COPD) treatment. A disadvantage is their sensitivity to humidity. In real life …

Dry powder inhaler (DPI) for pulmonary delivery is currently the primary treatment for asthma
and COPD (chronic obstructive pulmonary disease), an increasing number of combined …

Pulmonary drug delivery has gained great attention in local or systemic diseases therapy,
however it is still difficult to scale-up DPI production due to the complexity of interactions …

Most of the marketed dry powder inhalation (DPI) products are traditional, carrier-based
formulations with low drug concentrations deposited in the lung. However, due to their …

Objective: The aim was to study the stability of dry powder inhaler (DPI) formulations
containing antibiotic with different preparation ways–carrier-based, carrier-free, and novel …

Dry Powder Inhalers play a major role in today's treatment of various respiratory diseases. A
lot of effort has been put into the optimization of a device and the appropriate formulation …

The effects of propellant type, cosolvent content, and air humidity on the morphology and
solid phase of the particles produced from solution pressurized metered dose inhalers …