Natural product evodiamine and its derivatives represent a promising class of multi-target
antitumor agents. However, the clinical development of these compounds has been …

Hydroxyevodiamine is a multitargeting antitumor lead compound with excellent in vitro
activity. However, its in vivo antitumor potency is rather limited, which has hampered its …

Evodiamine, an alkaloid isolated from Evodia rutaecarpa, possesses potent anticancer
activity. Although many reports have elucidated the cytotoxic effects of evodiamine in a …

Melanoma is a common solid malignant tumor with a high frequency of metastasis and
relapse. Evodiamine (EVO), a natural small molecule, has recently attracted considerable …

Evodiamine is a major alkaloid component found in the fruit of Evodia rutaecarpa. It shows
the anti-proliferative potential against a wide range of cancers by suppressing cell growth …

The identification of anticancer active ingredients and their molecular targets in traditional
Chinese medicine is a great challenge in modern pharmacology research. Evodiamine is …

Traditional Chinese herbs are regarded as a new and promising source of potential anti-
cancer remedies and new chemotherapy adjuvants to enhance the efficacy of chemotherapy …

Evodiamine is one of the major bioactive compounds that have been isolated and purified
from the fruit of Evodiae fructus. Evodiamine exhibits antitumor activities against the human …

Evodiamine is a quinazolinocarboline alkaloid isolated from the fruits of traditional Chinese
herb Evodiae fructus. Previously, we identified N13-substituted evodiamine derivatives as …

Abstract Evodiamine (1), a biologically active alkaloid isolated from Evodia rutaecarpa
(known in Chinese as Wu‐Chu‐Yu), has antioxidant, anti‐inflammatory, and anticancer …