Roux's principle of bone functional adaptation postulates that bone tissue, and particularly
trabecular bone tissue, responds to mechanical stimuli by adjusting (modeling) its …

Most bone adaptation algorithms, that attempt to explain the connection between bone
morphology and loads, assume that bone is effectively isotropic. An isotropic material model …

Large-deformation bending and buckling have long been proposed as failure mechanisms
by which the strength of trabecular bone can be affected disproportionately to changes in …

Understanding the dependence of human trabecular bone strength behavior on anatomic
site provides insight into structure–function relationships and is essential to the increased …

Trabecular architecture plays a major role in bone mechanics. Osteoporosis leads to a
transition from a plate-like to a more rod-like trabecular morphology, which may contribute to …

Apparent yield strains for trabecular bone are uniform within an anatomic site but can vary
across site. The overall goal of this study was to characterize the contribution of inter-site …

Trabecular bone structure is crucial to normal mechanical behavior of bones. Studies have
shown that osteoporosis negatively affects trabecular bone structure, mainly by reducing …

Trabecular plates and rods determine apparent elastic modulus and yield strength of
trabecular bone, serving as important indicators of bone's mechanical integrity in health and …

Variations in yield strains for trabecular bone within a specific anatomic site are only a small
fraction of the substantial variations that exist for elastic modulus and strength, and yet the …

It is well established that bones functionally adapt by mechanisms that control tissue density,
whole bone geometry, and trabecular orientation. In this study, we propose the existence of …