Here, we found that Thioflavin T (ThT) could specifically bind with a G-GGG unit (named as
“Guanine Island”) in double stranded DNA (ds-DNA). Through stacking with G base via …

DNA sequences with guanine repeats can be induced to form G-quartets that adopt G-
quadruplex structures in the presence of thioflavin T (ThT). ThT plays a dual role of inducing …

Binding to the minor groove of calf-thymus DNA (ct-DNA) and strong binding in hydrophobic
pocket of bovine serum albumin (BSA), switched-on the fluorescence of smart fluorescent …

Abstract More than 700,000 G-rich sequences in the human genome are able to form G-
quadruplex (G4). Since G4 is closely relevant to a variety of essential biological regulatory …

The detection and targeting of both the mismatched and abasic DNA is highly important
which would ultimately help in designing new diagnostics and chemotherapeutics …

A novel fluorescent method for the detection of single nucleotide polymorphism (SNP) was
developed using a hairpin DNA containing nucleotide base analog pyrrolo-deoxycytidine (P …

We newly synthesized thioflavin T (ThT) analogs for which the methyl group at the N 3
position on the benzothiazole ring was replaced with either a ((p-(dimethylamino) benzoyl) …

Some mustard compounds (mustards) are highly toxic chemical warfare agents. Some are
explored as new anticancer drugs. Therefore, the fast, selective, and sensitive detection of …

Bind it! A ratiometric fluorescent probe based on conjugation of a DNA‐binding ligand with
an environmentally sensitive dye to probe hydrophobic grooves of the DNA helix was …

In molecular biology, understanding the functional and structural aspects of DNA requires
sequence-specific DNA binding probes. Especially, sequence-specific fluorescence probes …