Hypoxic-ischemic encephalopathy (HIE) is a major cause of mortality and morbidity in
neonates, with an estimated global incidence of 3/1,000 live births. HIE brain damage is …

Background Cerebral ischemia/reperfusion (I/R) injury contributes to mortality and morbidity
in preterm infants. Curcumin has been shown to exert neuro-protective effects in the central …

Cerebral ischemia/reperfusion (I/R) injury can result in different levels of cerebral
impairment, and in severe cases, death. Curcumin, an essential bioactive component of …

This study aimed to evaluate the effect of curcumin on brain hypoxic-ischemic (HI) damage
in neonatal rats and whether the phosphoinositide 3-kinase (PI3K)/Akt/vascular endothelial …

Hypoxic-ischemic encephalopathy is the leading cause of permanent brain injury in term
newborns and currently has no cure. Inflammatory processes play a key role in the …

Currently available pharmacological treatment of post-ischemia-reperfusion brain injury has
limited effectiveness. This review provides an assessment of the current state of …

Chronic intermittent hypoxia (CIH) is one of the main features of obstructive sleep apnea
(OSA), which is also commonly associated with neurocognitive impairments. The present …

Ischemic stroke is the leading cause of death and disability worldwide, and restoring the
blood flow to ischemic brain tissues is currently the main therapeutic strategy. However …

Background: Ischemic brain injury is among the most common causes of death and disability
in humans worldwide. Recent findings suggest that neural precursors in the adult …

Curcumin has previously demonstrated anti‑inflammatory, anti‑infective and immuno‑
suppressive effects. In the present study, whether the attenuating effects of curcumin against …