PLGA nanoparticle-based docetaxel/LY294002 drug delivery system enhances antitumor activities against gastric cancer
J Cai, K Qian, X Zuo, W Yue, Y Bian… - Journal of …, 2019 - journals.sagepub.com
Docetaxel (TXT) is acknowledged as one of the most important chemotherapy agents for
gastric cancer (GC). PI3K/AKT signaling is frequently activated in GC, and its inhibitor …
gastric cancer (GC). PI3K/AKT signaling is frequently activated in GC, and its inhibitor …
Development of novel PLGA nanoparticles with co‐encapsulation of docetaxel and abiraterone acetate for a highly efficient delivery into tumor cells
MB Sokol, ED Nikolskaya, NG Yabbarov… - … Research Part B …, 2019 - Wiley Online Library
Co‐encapsulation of abiraterone acetate (AbrA) and docetaxel (Dtx) in polymeric
nanoparticles as novel prototypes for prostate cancer treatment combining hormonal and …
nanoparticles as novel prototypes for prostate cancer treatment combining hormonal and …
[HTML][HTML] Superior in vitro anticancer effect of biomimetic paclitaxel and triptolide co-delivery system in gastric cancer
S Wang, H Jiang, J Wang, H Wu, T Wu… - Journal of Biomedical …, 2021 - ncbi.nlm.nih.gov
As a well-known anticancer drug, paclitaxel (PTX), a first-line chemotherapeutic agent,
remains unsatisfactory for gastric cancer therapy. It is reported that triptolide (TPL) could …
remains unsatisfactory for gastric cancer therapy. It is reported that triptolide (TPL) could …
iRGD Co-Administration with paclitaxel-loaded PLGA nanoparticles enhance targeting and antitumor effect in colorectal cancer treatment
L Li, M Yang, R Li, J Hu, L Yu… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Objective: To explore the targeting effect of PLGA-NP and iRGD co-administration with
PTXPLGA NP (PTX-PLGA+ iRGD) on colorectal cancer. Methods: Whether PLGA-NP co …
PTXPLGA NP (PTX-PLGA+ iRGD) on colorectal cancer. Methods: Whether PLGA-NP co …
Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and …
Intestinal cancers are the third most lethal cancers globally, beginning as polyps in the
intestine and spreading with a severe metastatic tendency. Chemotherapeutic drugs used in …
intestine and spreading with a severe metastatic tendency. Chemotherapeutic drugs used in …
Combination drug delivery with actively-targeted PLGA nanoparticles to overcome multidrug resistance in breast cancer
Drug resistance is a major obstacle reducing the efficacy of cancer chemotherapy that
decreases overall survival in breast cancer. P-glycoprotein (P-gp) inhibitors have potential to …
decreases overall survival in breast cancer. P-glycoprotein (P-gp) inhibitors have potential to …
Oral delivery of DMAB-modified docetaxel-loaded PLGA-TPGS nanoparticles for cancer chemotherapy
Three types of nanoparticle formulation from biodegradable PLGA-TPGS random copolymer
were developed in this research for oral administration of anticancer drugs, which include …
were developed in this research for oral administration of anticancer drugs, which include …
Facile fabrication of robust, hyaluronic acid-surfaced and disulfide-crosslinked PLGA nanoparticles for tumor-targeted and reduction-triggered release of docetaxel
X Wang, R Cheng, Z Zhong - Acta Biomaterialia, 2021 - Elsevier
It is highly tempting to develop high-efficacy targeted nanotherapeutics based on FDA
approved polymers like PLGA. Herein, we describe facile fabrication of robust, hyaluronic …
approved polymers like PLGA. Herein, we describe facile fabrication of robust, hyaluronic …
[HTML][HTML] Novel docetaxel chitosan-coated PLGA/PCL nanoparticles with magnified cytotoxicity and bioavailability
In the present study, docetaxel (DTX)-loaded poly (lactic-co-glycolic acid)(PLGA) and
polycaprolactone (PCL) nanoparticles were successfully prepared and coated with chitosan …
polycaprolactone (PCL) nanoparticles were successfully prepared and coated with chitosan …
The superior anticancer effect of reactive oxygen species-responsive paclitaxel nanoparticles is mediated through autophagic cell death
N Yu, J Li, PK Singh, D Ding, W Sun… - Journal of biomedical …, 2019 - ingentaconnect.com
Paclitaxel (Ptx) is a first-line chemotherapeutic drug for advanced gastric cancer. However,
the poor solubility of Ptx still limits its clinical application. Here, we designed a methoxy poly …
the poor solubility of Ptx still limits its clinical application. Here, we designed a methoxy poly …
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